SYNTHESIS, CHARACTERIZATION, AND BIOLOGICAL ACTIVITY OF A NEW CLASS OF DIALKYLPHOSPHORYLHYDRAZONE DERIVATIVES OF ISATIN

被引：6

作者：

Zampirolli, Leticia Silotti ^{[1
]}

de Lemos, Marcela Jacques ^{[1
]}

Goncalves, Vinicius Tomaz ^{[1
,2
]}

Alves de Souza, Marco Andre ^{[1
]}

de Souza, Sonia Regina ^{[1
]}

Rumjanek, Victor Marcos ^{[1
]}

DaCosta, Joao Batista Neves ^{[1
]}

机构：

[1] Univ Fed Rural Rio de Janeiro, Inst Ciencias Exatas, Dept Quim, BR-23890000 Seropedica, RJ, Brazil

[2] Ctr Fed Educ Tecnol Celso Suckow da Fonseca, Itaguai, RJ, Brazil

来源：

QUIMICA NOVA | 2014年 / 37卷 / 06期

关键词：

dialkylphosphorylhydrazones; isatins; biological activity; NATURAL-PRODUCTS; INHIBITION; PROTEINS; GROWTH;

D O I：

10.5935/0100-4042.20140162

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Sixteen dialkylphosphorylhydrazones were synthesized by condensation of phosphorylhydrazines with substituted isatins. Products were characterized by FTIR, H-1-NMR, C-13-NMR, and P-31-NMR. Fungicidal activities of these compounds against Rhizoctonia solani and Fusarium oxysporum were also evaluated. Some compounds inhibited the growth of Rhizoctonia solani and Fusarium oxysporum by 43% and 51%, respectively. These compounds exhibited no effects on germination of lettuce seeds (Lactuca sativa L).

引用

页码：989 / U120

页数：46

共 50 条

[31] Synthesis, Characterization and Biological activity of mixed ligand Dimedon and Isatin with metal complex
Al-Dulaimi, Marwah M.
Al-Obaidi, Omar H.
JOURNAL OF WILDLIFE AND BIODIVERSITY, 2023, 7 : 138 - 155
[32] Synthesis, characterization and biological activity of Ni, Cu and Zn complexes of isatin hydrazones
Rodrìguez-Argüelles, MC
Ferrari, MB
Bisceglie, F
Pelizzi, C
Pelosi, G
Pinelli, S
Sassi, M
JOURNAL OF INORGANIC BIOCHEMISTRY, 2004, 98 (02) : 313 - 321
[33] Synthesis, Biological Activity and Docking Study of Isatin Hydrazone Derivatives as Potential α-Glucosidase Inhibitors
Wang, Jing
Wang, Guangcheng
Xie, Zhenzhen
Peng, Yaping
Li, Luyao
Deng, Bing
Chen, Ming
Chen, Shan
Li, Wenbiao
LATIN AMERICAN JOURNAL OF PHARMACY, 2017, 36 (08): : 1533 - 1538
[34] Synthesis, computational studies and biological activity of oxamohydrazide derivatives bearing isatin and ferrocene scaffolds
Altowyan, Mezna Saleh
Ali, M.
Soliman, Saied M.
Al-Majid, Abdullah Mohammed
Islam, Mohammad Shahidul
Yousuf, Sammer
Choudhary, M. Iqbal
Ghabbour, Hazem A.
Barakat, Assem
JOURNAL OF MOLECULAR STRUCTURE, 2020, 1202
[35] Synthesis and in vitro cytotoxic activity of isatin derivatives
Nagarajan, G.
Balasubramaniam, V.
Manjunath, K. S.
Krishna, E. Rama
Reddy, K. Pradeep Kumar
Reddy, E. Krupakar
Girua, K.
ASIAN JOURNAL OF CHEMISTRY, 2008, 20 (03) : 1665 - 1669
[36] The synthesis of new derivatives of 1,4-dihydropyridines class with a potential biological activity
Ilie, C
Guta, R
Nanau-Andreescu, D
Putina, G
Ghita, C
Nita, S
Caproiu, MT
Draghici, C
REVISTA DE CHIMIE, 2002, 53 (07): : 513 - 518
[37] Synthesis, Characterization, and Study the Biological Activity of New Di-azetidinone Derivatives
Aziz, Dhurgham
Majeed, Mohauman Mohammed
Salim, Ahmed Thamer
JOURNAL OF POPULATION THERAPEUTICS AND CLINICAL PHARMACOLOGY, 2023, 30 (07): : E349 - E359
[38] Synthesis, Characterization, Biological Activity and Quantum Chemical Calculations of New Oxadiazole Derivatives
Merdas, Samia Mezhr
EGYPTIAN JOURNAL OF CHEMISTRY, 2022, 65 (05): : 635 - 645
[39] Synthesis, characterization, and biological activity of some new benzoic acid and thiazoloacridine derivatives
Patel, Nilav A.
Surti, Sandip C.
Patel, R. G.
Patel, M. P.
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2008, 183 (09) : 2191 - 2203
[40] Synthesis, characterization, quantum chemical calculations and antioxidant activity of new bis-isatin carbohydrazone and thiocarbohydrazone derivatives
Muglu, Halit
Cavus, M. Serdar
Bakir, Temelkan
Yakan, Hasan
JOURNAL OF MOLECULAR STRUCTURE, 2019, 1196 : 819 - 827

← 1 2 3 4 5 →