Synthesis and biological activity of high-molecular N-glycosides

被引：1
|
作者：
Shul'tsev, A. L. [1 ]
机构：
[1] Russian Acad Sci, Inst Macromol Cpds, St Petersburg 199004, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2015年 / 85卷 / 10期
关键词：
p-aminostyrene; N-glycosides; carbon chain polymers; biological activity;
D O I：
10.1134/S1070363215100229
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new synthetic approach to high molecular N-glycosides has been developed on the basis of radical polymerization of vinyl-containing N-glycosides. Homo- and copolymers derived from N-(D-glucopyranosyl)-, N-(D-mannopyranosyl)-, and N-(L-rhamnopyranosyl)-4-vinylaniline have been synthesized and characterized. It has been found for the first time that polymeric N-glycosides exhibit antibacterial and immunomodulatory activity.
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页码：2361 / 2365
页数：5
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