One-Pot Iodination of Hydroxypyridines

被引：23
|
作者：
Maloney, Kevin M. [1 ]
Nwakpuda, Emily [1 ]
Kuethe, Jeffrey T. [1 ]
Yin, Jingjun [1 ]
机构：
[1] Merck & Co Inc, Dept Proc Res, Rahway, NJ 07065 USA
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 74卷 / 14期
关键词：
PYRIDINES;
D O I：
10.1021/jo900726f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A one-pot, high-yielding iodination of hydroxypyridines and hydroxyquinolines is described. The iodination proceeds under mild conditions, and the products are obtained in high yield without the need for chromatographic purification. In addition, the iodination works on both 2- and 4-hydroxypyridines and -hydroxyquinolines.
引用
收藏
页码：5111 / 5114
页数：4
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