Bioactive steroidal saponins from Smilax medica

被引：15
|
作者：
Sautour, M.
Miyarrioto, T.
Lacaille-Dubois, M. -A.
机构：
[1] Univ Bourgogne, Fac Pharm, UPRES EA 3660, Unite UMIB,Lab Pharmacog, F-21079 Dijon, France
[2] Kyushu Univ, Grad Sch Pharmaceut Sci, Fukuoka, Japan
来源：
PLANTA MEDICA | 2006年 / 72卷 / 07期
关键词：
D O I：
10.1055/s-2006-931582
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new spirostanol saponins (1 and 2) were isolated from the roots of Smilax medica, together with the known smilagenin 3-O-beta-D-glucopyranoside (3). Their structures were determined by spectroscopic methods including 1D- and 2D-NMR experiments. Compounds 1 and 2 exhibited antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis (MICs between 6.25 and 50 mu g/mL) whereas 3 was inactive.
引用
收藏
页码：667 / 670
页数：4
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