Association study of adenosine A2a receptor (1976C>T) genetic polymorphism and mood disorders and age of onset

被引：10
|
作者：
Tsai, Shih-Jen
Hong, Chen-Jee
Hou, Sheue-Jane
Yen, Feng-Chang
机构：
[1] Taipei Vet Gen Hosp, Dept Psychiat, Taipei 11217, Taiwan
[2] Natl Yang Ming Univ, Sch Med, Div Psychiat, Taipei 112, Taiwan
[3] Cheng Hsin Rehabil & Med Ctr, Div Psychiat, Taipei, Taiwan
来源：
PSYCHIATRIC GENETICS | 2006年 / 16卷 / 05期
关键词：
mood disorders; adenosine A2a receptor; polymorphism;
D O I：
10.1097/01.ypg.0000218627.26622.eb
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Evidence suggests that the adenosine A2a receptor (A2aAR) may be implicated in the pathogenesis of mood disorders. We tested the hypothesis that the A2aAR 1976C > T genetic variant confers susceptibility to mood disorders by comparing 192 mood disorder patients and 216 normal controls. The distribution of the A2aAR genotypes and alleles did not differ significantly comparing the two groups, suggesting that it is unlikely that the A2aAR 1976C > T polymorphism plays a major role in the development of mood disorders. Psychiatr Genet 16:185 (c) 2006 Lippincott Williams & Wilkins.
引用
收藏
页码：185 / 185
页数：1
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