Knowledge Representation for Multi-Scale Physiology Route Modeling

被引:7
|
作者
Kokash, Natallia [1 ]
de Bono, Bernard [1 ,2 ]
机构
[1] Peoples Friendship Univ Russia, Moscow, Russia
[2] Univ Auckland, Auckland Bioengn Inst, Auckland, New Zealand
关键词
physiology; multi-scale model; knowledge management; anatomy; connectivity; ontology;
D O I
10.3389/fninf.2021.560050
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We present a framework for the topological and semantic assembly of multiscale physiology route maps. The framework, called ApiNATOMY, consists of a knowledge representation (KR) model and a set of knowledge management (KM) tools. Using examples of ApiNATOMY route maps, we present a KR format that is suitable for the analysis and visualization by KM tools. The conceptual KR model provides a simple method for physiology experts to capture process interactions among anatomical entities. In this paper, we outline the KR model, modeling format, and the KM procedures to translate concise abstraction-based specifications into fully instantiated models of physiology processes.
引用
收藏
页数:17
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