Synthesis of new CF3-containing pyridazinone and lactam derivatives

被引：0
|
作者：
Dinoiu, Vasile [1 ]
机构：
[1] Univ Rouen, IRCOF, F-76130 Mont St Aignan, France
[2] Roumanian Acad, Inst Organ Chem CD Nenitzescu, Bucharest 77141, Romania
来源：
REVUE ROUMAINE DE CHIMIE | 2006年 / 51卷 / 7-8期
关键词：
trifluoromethyl; gamma-ketothioester; furan; lactam; pyridazinone;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The paper presents the convertion of the bifunctional intermediate gamma-keto-thioester (6), into new of pyridazin-3-ones (8) and lactam (9), by reaction with hydrazine derivatives. The structures of all new compounds were ascribed using I D (F-19, H-1, C-13) NMR data that confirmed their structure. The possible reaction mechanisms for the synthesis of pyridazinones (8) and lactam (9) are presented.
引用
收藏
页码：623 / 628
页数：6
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