An 'Arms Race' between the Nonsense-mediated mRNA Decay Pathway and Viral Infections

被引：14
|
作者：
Leon, Kristoffer [1 ,2 ]
Ott, Melanie [1 ,2 ]
机构：
[1] J David Gladstone Inst, San Francisco, CA USA
[2] Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
来源：
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2021年 / 111卷
关键词：
Viruses; RNA biology; Nonsense-mediated mRNA decay; Anti-viral response; CAULIFLOWER-MOSAIC-VIRUS; EXON-JUNCTION COMPLEX; PLANT-PATHOGEN; RECRUITS UPF1; GAG GENE; SURVEILLANCE; STABILITY; PROTEIN; CODONS; PHOSPHORYLATION;
D O I：
10.1016/j.semcdb.2020.05.018
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The Nonsense-mediated mRNA Decay (NMD) pathway is an RNA quality control pathway conserved among eukaryotic cells. While historically thought to predominantly recognize transcripts with premature termination codons, it is now known that the NMD pathway plays a variety of roles, from homeostatic events to control of viral pathogens. In this review we highlight the reciprocal interactions between the host NMD pathway and viral pathogens, which have shaped both the host antiviral defense and viral pathogenesis.
引用
收藏
页码：101 / 107
页数：7
相关论文
共 50 条
  • [21] Nonsense-mediated mRNA decay (NMD) mechanisms
    Saverio Brogna
    Jikai Wen
    Nature Structural & Molecular Biology, 2009, 16 : 107 - 113
  • [22] Cellular variability of nonsense-mediated mRNA decay
    Hanae Sato
    Robert H. Singer
    Nature Communications, 12
  • [23] Nonsense-mediated mRNA decay (NMD) mechanisms
    Brogna, Saverio
    Wen, Jikai
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2009, 16 (02) : 107 - 113
  • [24] Cellular variability of nonsense-mediated mRNA decay
    Sato, Hanae
    Singer, Robert H.
    NATURE COMMUNICATIONS, 2021, 12 (01)
  • [25] Nonsense-mediated decay of human HEXA mRNA
    Rajavel, KS
    Neufeld, EF
    MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (16) : 5512 - 5519
  • [26] The mammalian nonsense-mediated mRNA decay pathway: To decay or not to decay! Which players make the decision?
    Silva, Ana Luisa
    Romao, Luisa
    FEBS LETTERS, 2009, 583 (03): : 499 - 505
  • [27] Stress and the nonsense-mediated RNA decay pathway
    Alexandra E. Goetz
    Miles Wilkinson
    Cellular and Molecular Life Sciences, 2017, 74 : 3509 - 3531
  • [28] The nonsense-mediated decay RNA surveillance pathway
    Chang, Yao-Fu
    Imam, J. Saadi
    Wilkinson, Miles E.
    ANNUAL REVIEW OF BIOCHEMISTRY, 2007, 76 : 51 - 74
  • [29] Mechanism and regulation of the nonsense-mediated decay pathway
    Hug, Nele
    Longman, Dasa
    Caceres, Javier F.
    NUCLEIC ACIDS RESEARCH, 2016, 44 (04) : 1483 - 1495
  • [30] Gene set coregulated by the Saccharomyces cerevisiae nonsense-mediated mRNA decay pathway
    Taylor, R
    Kebaara, BW
    Nazarenus, T
    Jones, A
    Yamanaka, R
    Uhrenholdt, R
    Wendler, JP
    Atkin, AL
    EUKARYOTIC CELL, 2005, 4 (12) : 2066 - 2077
12345