Dual inhibition of the MAPK pathway by combination targeted therapy: a phase I trial of sorafenib (SOR) and erlotinib (ERL) in advanced solid tumors

被引:5
|
作者
Duran, I.
Hotte, S.
Chen, E.
Hirte, H.
MacLean, M.
Turner, S.
Pond, G.
Wright, J.
Dancey, J.
Siul, L.
机构
[1] Princess Margaret Hosp Phase II Consortium, Toronto, ON, Canada
[2] Natl Canc Inst, Bethesda, MD USA
来源
EJC SUPPLEMENTS | 2006年 / 4卷 / 12期
关键词
D O I
10.1016/S1359-6349(06)70555-9
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
550
引用
收藏
页码:167 / 167
页数:1
相关论文
共 50 条
  • [21] Phase I study of pemetrexed with sorafenib in advanced solid tumors
    Poklepovic, Andrew
    Gordon, Sarah
    Shafer, Danielle A.
    Roberts, John D.
    Bose, Prithviraj
    Geyer, Charles E., Jr.
    McGuire, William P.
    Tombes, Mary Beth
    Shrader, Ellen
    Strickler, Katie
    Quigley, Maria
    Wan, Wen
    Kmieciak, Maciej
    Massey, H. Davis
    Booth, Laurence
    Moran, Richard G.
    Dent, Paul
    ONCOTARGET, 2016, 7 (27): : 42625 - 42638
  • [22] A phase I trial of erlotinib and bexarotene as a targeted combination therapy for aerodigestive tract cancers.
    Dragnev, KH
    Petty, WJ
    Shah, S
    Carey, MA
    Disalvo, WM
    Williams, I
    Rigas, JR
    Dmitrovsky, E
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) : 643S - 643S
  • [23] Dual Inhibition of the Epidermal Growth Factor Receptor Pathway with Cetuximab and Erlotinib: A Phase I Study in Patients with Advanced Solid Malignancies
    Guarino, Michael J.
    Schneider, Charles J.
    Hosford, Martha A.
    Brahmer, Julie R.
    Rudin, Charles M.
    Finckenstein, Friedrich Graf
    Philip-Norton, Robyn E.
    Lu, Haolan
    Weber, Martin R.
    Ettinger, David S.
    ONCOLOGIST, 2009, 14 (02): : 119 - 124
  • [24] SORAVE trial: Phase I sorafenib and everolimus in solid tumors
    Nogova, L.
    Scheffler, M.
    Papachristou, I.
    Mattonet, C.
    Krais, R.
    Katay, I.
    Mallmann, P.
    Fuhr, U.
    Dietlein, M.
    Wolf, J.
    JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (15)
  • [25] SORAVE trial: Phase I sorafenib and everolimus in solid tumors
    Nogova, L.
    Scheffler, M.
    Papachristou, I
    Mattonet, C.
    Krais, R.
    Dietlein, M.
    Fuhr, U.
    Mallmann, P.
    Wolf, J.
    ONKOLOGIE, 2010, 33 : 61 - 62
  • [26] A Phase I Clinical Trial of Safingol in Combination with Cisplatin in Advanced Solid Tumors
    Dickson, Mark A.
    Carvajal, Richard D.
    Merrill, Alfred H., Jr.
    Gonen, Mithat
    Cane, Lauren M.
    Schwartz, Gary K.
    CLINICAL CANCER RESEARCH, 2011, 17 (08) : 2484 - 2492
  • [27] Bortezomib in combination with celecoxib in patients with advanced solid tumors: a phase I trial
    John Hayslip
    Uzair Chaudhary
    Mark Green
    Mario Meyer
    Steven Dunder
    Carol Sherman
    Shanta Salzer
    Andrew Kraft
    Alberto J Montero
    BMC Cancer, 7
  • [28] A phase I trial of oxaliplatin in combination with docetaxel in patients with advanced solid tumors
    Syma Iqbal
    Heinz-Josef Lenz
    David R. Gandara
    Stephen I. Shibata
    Susan Groshen
    Timothy W. Synold
    Edward M. Newman
    Cancer Chemotherapy and Pharmacology, 2013, 72 : 85 - 91
  • [29] A phase I trial of gemcitabine in combination with patupilone in patients with advanced solid tumors
    William Schelman
    Sherry Morgan-Meadows
    Howard Bailey
    Kyle Holen
    James P. Thomas
    Jens Eickhoff
    Heidi Brandon
    Kate Oliver
    Dona Alberti
    George Wilding
    Cancer Chemotherapy and Pharmacology, 2008, 62 : 727 - 733
  • [30] A phase I trial of oxaliplatin in combination with docetaxel in patients with advanced solid tumors
    Iqbal, Syma
    Lenz, Heinz-Josef
    Gandara, David R.
    Shibata, Stephen I.
    Groshen, Susan
    Synold, Timothy W.
    Newman, Edward M.
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 72 (01) : 85 - 91