Copper-Catalyzed Hydroalkylation of Alkynes: Addition of sp3 C-H Bonds Across Carbon-Carbon Triple Bonds

被引：35
|
作者：
Huang, Lehao [1 ]
Cheng, Kai [1 ]
Yao, Bangben [1 ]
Zhao, Jinlong [1 ]
Zhang, Yuhong [1 ]
机构：
[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China
来源：
SYNTHESIS-STUTTGART | 2009年 / 20期
关键词：
C-H activation; copper; addition reactions; alkynes; tert-butyl hydroperoxide; OXIDATIVE CYANATION; HYDROGEN-PEROXIDE; TERTIARY-AMINES; FUNCTIONALIZATION; ADJACENT; ARYLATION; ALKENYLATION; ACTIVATION; HYDROARYLATION; ALKYNYLATION;
D O I：
10.1055/s-0029-1216991
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The regioselective copper-catalyzed addition of sp(3) C-H bonds adjacent to an oxygen atom to various alkynes has been accomplished under mild reactions conditions in the presence of tert-butyl hydroperoxide to give the corresponding alkenylated products.
引用
收藏
页码：3504 / 3510
页数：7
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