A Novel T-cell Population Expressing the Ectoenzymes CD38 and CD39 is Associated with Melanoma Patient Non-Response to Immunotherapy.

被引:0
|
作者
Mitra, Ankita [1 ]
Woods, David M. [2 ]
Rao, Anjali [3 ]
Laino, Andressa S. [4 ]
Winters, Aidan [5 ]
Yanai, Itai [3 ]
Chattopadhyay, Pratip K. [1 ]
Weber, Jeffrey S. [1 ]
机构
[1] NYU Langone Hlth, Laura & Isaac Perlmutter Canc Ctr, New York, NY USA
[2] Univ Colorado, Sch Med, Div Med Oncol, Dept Med, Aurora, CO USA
[3] NYU, Sch Med, Insitute Computat Med, New York, NY 10003 USA
[4] Moderna Therapeut, Cambridge, MA USA
[5] Univ Calif San Francisco, San Francisco, CA 94143 USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PO030
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Characterization of a novel Melan-A/Mart-1 CD4T cell epitope in a vaccinated melanoma patient developing a tumour-specific CTL response
    Braun, M.
    Jandus, C.
    Baumgartner, P.
    Schwarz, K.
    Bachmann, M.
    Speiser, D.
    Romero, P.
    SWISS MEDICAL WEEKLY, 2009, 139 (9-10) : 13S - 13S
  • [42] CD4+ T-CELL CLONES SPECIFIC FOR THE HUMAN P97 MELANOMA-ASSOCIATED ANTIGEN CAN ERADICATE PULMONARY METASTASES FROM A MURINE TUMOR EXPRESSING THE P97 ANTIGEN
    KAHN, M
    SUGAWARA, H
    MCGOWAN, P
    OKUNO, K
    NAGOYA, S
    HELLSTROM, KE
    HELLSTROM, I
    GREENBERG, P
    JOURNAL OF IMMUNOLOGY, 1991, 146 (09): : 3235 - 3241
  • [43] A novel noninvasive biomarker based on peripheral PD-1posi CD8 T-cell receptor repertoire correlated with clinical outcomes to immunotherapy in non-small cell lung cancer.
    Han, Jie-Fei
    Wang, Zhijie
    Bai, Hua
    Chen, Si
    Wang, Yuqi
    Dean, Jianchun
    Wang, Jie
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [44] The novel coreceptor CD8α:MyD88 enhances T-cell proliferation, activation, and antitumor response at low-dose IL-2 in B16 melanoma
    Cao, Phoebe
    Chen, Jiangli
    Ciavattone, Nicholas
    Davila, Eduardo
    JOURNAL OF IMMUNOLOGY, 2022, 208 (01):
  • [45] Increased systemic activated CD4+T cells and non-classical monocytes are associated with improved immunotherapy response and progression-free survival in non-small cell lung cancer patients
    Figueiredo, Amanda B.
    Iasbeke Ferreira, Stephanie M.
    Evangelista, Guilherme F. B.
    Santos, Iasmim P.
    Kuil, Larissa M.
    Cavalcanti, Clara M.
    Morais, Katia L. P.
    Galdino, Nayane A. L.
    Lopes, Ananda D.
    Freitas, Helano C.
    Gross, Jefferson L.
    Lopes Pinto, Clovis A.
    Chojniak, Rubens
    Cordeiro de Lima, Vladmir C.
    Gollob, Kenneth J.
    CANCER IMMUNOLOGY RESEARCH, 2022, 10 (12)
  • [46] Transcend NHL 001: Immunotherapy with the CD19-Directed CAR T-Cell Product JCAR017 Results in High Complete Response Rates in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
    Abramson, Jeremy S.
    Palomba, Lia
    Gordon, Leo I.
    Lunning, Matthew
    Arnason, Jon
    Forero-Torres, Andres
    Albertson, Tina M.
    Exton, Victoria Shaw
    Sutherland, Claire
    Xie, Benhuai
    Snodgrass, Susan
    Siddiqi, Tanya
    BLOOD, 2016, 128 (22)
  • [47] Identification of a high-risk immunogenic prostate cancer patient subset as candidates for T-cell engager immunotherapy and the introduction of a novel albumin-fused anti-CD3 × anti-PSMA bispecific design
    Eske N. Glud
    Martin Rasmussen
    Yonghui Zhang
    Ole A. Mandrup
    Paul Vinu Salachan
    Michael Borre
    Karina Dalsgaard Sørensen
    Kenneth A. Howard
    British Journal of Cancer, 2022, 127 : 2186 - 2197
  • [48] Sustained CD8+ T-cell immune response to a novel immunodominant HLA-B*0702-associated epitope derived from an Epstein-Barr virus helicase-primase-associated protein
    Turcanová, V
    Höllsberg, P
    JOURNAL OF MEDICAL VIROLOGY, 2004, 72 (04) : 635 - 645
  • [49] Multivariate Analyses Indicate That the Cytokine Response to Lymphodepletion May be Better Associated Than Lymphodepletion Intensity with the Efficacy of CD19 CAR-T Cell Immunotherapy for Aggressive B-Cell Non-Hodgkin Lymphoma
    Hirayama, Alexandre V.
    Gauthier, Jordan
    Hay, Kevin A.
    Voutsinas, Jenna M.
    Wu, Qian
    Gooley, Ted A.
    Li, Daniel
    Sheih, Alyssa
    Purushe, Janaki
    Cherian, Sindhu
    Chen, Xueyan
    Pender, Barbara S.
    Hawkins, Reed M.
    Vakil, Aesha
    Phi, Tinh-Doan
    Steinmetz, Rachel N.
    Acharya, Utkarsh H.
    Chapuis, Aude G.
    Dhawale, Tejaswini
    Hendrie, Paul C.
    Kiem, Hans-Peter
    Lynch, Ryan C.
    Ramos, Jorge
    Shadman, Mazyar
    Till, Brian G.
    Riddell, Stanley R.
    Maloney, David G.
    Turtle, Cameron J.
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2019, 25 (03)
  • [50] The associations among coping, nadir CD4+ T-cell count, and non-HIV-related variables with health-related quality of life among an ambulatory HIV-positive patient population
    Carl Armon
    Kenneth Lichtenstein
    Quality of Life Research, 2012, 21 : 993 - 1003