Ruthenium-catalyzed selective imine synthesis from nitriles and secondary alcohols under hydrogen acceptor- and base-free conditions

被引：16
|
作者：
Kim, Daeun [1 ]
Kang, Byungjoon [1 ]
Hong, Soon Hyeok [1 ]
机构：
[1] Seoul Natl Univ, Coll Nat Sci, Dept Chem, Seoul 08826, South Korea
来源：
ORGANIC CHEMISTRY FRONTIERS | 2016年 / 3卷 / 04期
基金：
新加坡国家研究基金会;
关键词：
AEROBIC OXIDATIVE SYNTHESIS; ONE-POT SYNTHESIS; METAL-FREE; PRIMARY AMINES; MILD CONDITIONS; AMIDE SYNTHESIS; NEAT CONDITIONS; DEHYDROGENATION; COMPLEX; BONDS;
D O I：
10.1039/c5qo00378d
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We report a method for the selective synthesis of imines from nitriles and secondary alcohols using a hydrogen-transfer strategy. The imine bond is efficiently formed between the nitrogen atom of nitrile and the alpha-carbon of secondary alcohol, catalyzed by a ruthenium dihydride complex with pyridine as a stabilizing ligand.
引用
收藏
页码：475 / 479
页数：5
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