PML-RARα kills U937 cells:: A novel activity of PML-RARα that may contribute to APL pathogenesis.

被引:0
|
作者
Lane, AA
Westervelt, P
Ley, TJ
机构
[1] Washington Univ, St Louis, MO 63130 USA
[2] Univ Massachusetts, Med Ctr, Worcester, MA USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
2111
引用
收藏
页码:538A / 538A
页数:1
相关论文
共 50 条
  • [31] RT-PCR检测氧化砷治疗APL复发患者的PML-RARα融合基因
    黄秋花
    倪建华
    唐玮
    沈志祥
    陈国强
    上海医学, 1998, (05) : 5 - 7
  • [32] A Protease-Resistant PML-RARα Has Increased Leukemogenic Potential in a Murine Model of Acute Promyelocytic Leukemia (APL)
    Uy, Geoffrey L.
    Welch, John S.
    Lane, Andrew A.
    Ley, Timothy J.
    BLOOD, 2008, 112 (11) : 344 - 344
  • [33] A vector expressing PML-RARα fused to GM-CSF is an effective DNA vaccine for inducing specific immune response to APL cells
    Li, Yangqiu
    Cen, Dongzhi
    Hu, Gang
    Zhou, Yubing
    Chen, Shaohua
    Yang, Lijian
    Przybylski, Grzegorz K.
    Schmidt, Christian A.
    BLOOD, 2007, 110 (11) : 295B - 295B
  • [34] Disruption of the PHRF1 Tumor Suppressor Network by PML-RARα Drives Acute Promyelocytic Leukemia Pathogenesis
    Prunier, Celine
    Zhang, Ming-Zhu
    Kumar, Santosh
    Levy, Laurence
    Ferrigno, Olivier
    Tzivion, Guri
    Atfi, Azeddine
    CELL REPORTS, 2015, 10 (06): : 883 - 890
  • [35] Gene transactivation without direct DNA binding defines a novel gain-of-function for PML-RARα
    van Wageningen, Sake
    Breerns-de Ridder, Marleen C.
    Nigten, Jeannet
    Nikoloski, Gorica
    Erpelinck-Verschueren, Claudia A. J.
    Loewenberg, Bob
    de Witte, Theo
    Tenen, Daniel G.
    van der Reijden, Bert A.
    Jansen, Joop H.
    BLOOD, 2008, 111 (03) : 1634 - 1643
  • [36] PML-RARα sequesters RXRα to sites within the nucleus distinct from RARα and reduces RXRα intranuclear mobility in live cells.
    Shuo, D
    Stenoien, DL
    Mancini, MA
    Tweardy, DJ
    BLOOD, 2002, 100 (11) : 529A - 530A
  • [37] MER1, a novel organic arsenic derivative, has potent PML-RARα- independent cytotoxic activity against leukemia cells
    Mirna Golemovic
    Alfonso Quintás-Cardama
    Taghi Manshouri
    Nada Orsolic
    Hatice Duzkale
    Mary Johansen
    Emil J. Freireich
    Hagop Kantarjian
    Ralph A. Zingaro
    Srdan Verstovsek
    Investigational New Drugs, 2010, 28 : 402 - 412
  • [38] MER1, a novel organic arsenic derivative, has potent PML-RARα- independent cytotoxic activity against leukemia cells
    Golemovic, Mirna
    Quintas-Cardama, Alfonso
    Manshouri, Taghi
    Orsolic, Nada
    Duzkale, Hatice
    Johansen, Mary
    Freireich, Emil J.
    Kantarjian, Hagop
    Zingaro, Ralph A.
    Verstovsek, Srdan
    INVESTIGATIONAL NEW DRUGS, 2010, 28 (04) : 402 - 412
  • [39] Therapeutic trials with retinoic acid and arsenic trioxide (AsO3) in PML-RAR alpha and PLZF-RAR alpha transgenic mice as models of APL
    He, LZ
    Peruzzi, D
    Tribioli, C
    Warrell, RP
    Pandolfi, PP
    BLOOD, 1997, 90 (10) : 825 - 825
  • [40] Tyrosine kinase inhibitor ST1571 potentiates the pharmacologic activity of retinoic acid in acute promyelocytic leukemia cells:: effects on the degradation of RARα and PML-RARα
    Gianni', M
    Kalaç, Y
    Ponzanelli, I
    Rambaldi, A
    Terao, M
    Garattini, E
    BLOOD, 2001, 97 (10) : 3234 - 3243