Synthesis of methyl 2-acetylamino-5-(1,3-dithian-2-yl)thiazole-4-carboxylate

被引：0
|
作者：
Feliu, L
Ajana, W
Joule, JA
LopezCalahorra, F
Alvarez, M
机构：
[1] UNIV MANCHESTER,DEPT CHEM,MANCHESTER M13 9PL,LANCS,ENGLAND
[2] UNIV BARCELONA,FAC QUIM,DEPT QUIM ORGAN,E-08028 BARCELONA,SPAIN
来源：
HETEROCYCLES | 1997年 / 45卷 / 07期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of methyl 2-acetylamino-5-(1,3-dithian-2-yl)thiazole-4-carboxylate (4) by formylation of a 4-substituted thiazole and then reaction with 1,3-propanedithiol are described. The utility of different ortho-directing groups (ODGs) for the lithiation of the thiazole 4-position has been studied.
引用
收藏
页码：1299 / 1308
页数：10
相关论文
共 50 条
  • [21] Synthesis of new 2-(1,3-dithianyl)phenols and hexakis-[p-(1,3-dithian-2-yl)phenoxy]cyclotriphosphazene
    Ladislav, S
    Jozefina, Z
    Nadezda, P
    MOLECULES, 1997, 2 (01) : 7 - 10
  • [22] 2-(1,3-Dithian-2-yl)benzaldehyde and N-{2-[2-(1,3-dioxan-2-yl)phenoxy]ethyl}phthalimide
    Jene, Paul G.
    Ibers, James A.
    Acta Crystallographica, Section C: Crystal Structure Communications, 2000, 56 (06) : 705 - 707
  • [23] Carbanionic displacement reactions at phosphorus: Synthesis and reactivity of 5,5-dimethyl-2-oxo-2-(1,3-dithian-2-yl)-1,3,2-dioxaphosphorinane
    Iorga, B
    Mouries, V
    Savignac, P
    BULLETIN DE LA SOCIETE CHIMIQUE DE FRANCE, 1997, 134 (10-11): : 891 - 895
  • [24] 2-(1,3-Dithian-2-yl)benzaldehyde and N-{2-[2-(1,3-dioxan-2-yl)phenoxy]-ethyl}phthalimide
    Jene, PG
    Ibers, JA
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 2000, 56 : 705 - 707
  • [25] SYNTHESIS AND REACTIVITY OF 2-(1,3-DITHIAN-2-YL)INDOLES .4. INFLUENCE OF THE N,N-DIETHYLCARBAMOYL INDOLE PROTECTING GROUP
    CASTELLS, J
    TROIN, Y
    DIEZ, A
    RUBIRALTA, M
    GRIERSON, DS
    HUSSON, HP
    TETRAHEDRON, 1991, 47 (37) : 7911 - 7924
  • [26] SYNTHETIC APPLICATIONS OF 2-(1,3-DITHIAN-2-YL)INDOLES .5. ASYMMETRIC-SYNTHESIS OF DASYCARPIDONE-TYPE INDOLE ALKALOIDS
    MICOUIN, L
    DIEZ, A
    CASTELLS, J
    LOPEZ, D
    RUBIRALTA, M
    QUIRION, JC
    HUSSON, HP
    TETRAHEDRON LETTERS, 1995, 36 (10) : 1693 - 1696
  • [27] SYNTHETIC APPLICATIONS OF 2-(1,3-DITHIAN-2-YL)INDOLES - A NEW SYNTHETIC APPROACH TO STRYCHNOS ALKALOIDS
    RUBIRALTA, M
    TORRENS, A
    REIG, I
    GRIERSON, DS
    HUSSON, HP
    HETEROCYCLES, 1989, 29 (11) : 2121 - 2133
  • [28] SYNTHETIC APPLICATIONS OF 2-(1,3-DITHIAN-2-YL)INDOLES .4. NEW SYNTHESIS OF THE TETRACYCLIC ABED RING-SYSTEM OF STRYCHNOS ALKALOIDS
    DIEZ, A
    CASTELLS, J
    FORNS, P
    RUBIRALTA, M
    GRIERSON, DS
    HUSSON, HP
    SOLANS, X
    FONTBARDIA, M
    TETRAHEDRON, 1994, 50 (22) : 6585 - 6602
  • [29] Synthesis and Crystal Structure of Methyl 2-(Diphenylamino)-4-phenyl-1,3-thiazole-5-carboxylate
    Ali Souldozi
    Seyed Hamid Reza Shojaei
    Ali Ramazani
    Katarzyna lepokura
    Tadeusz Lis
    结构化学, 2013, 32 (01) : 82 - 88
  • [30] Synthesis and Crystal Structure of Methyl 2-(Diphenylamino)-4-phenyl-1,3-thiazole-5-carboxylate
    Souldozi, Ali
    Shojaei, Seyed Hamid Reza
    Ramazani, Ali
    Slepokura, Katarzyna
    Lis, Tadeusz
    CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2013, 32 (01) : 82 - 88
12345