Dual C-H activation: Rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone

被引：9
|
作者：
Zhang, Qijing [1 ]
Li, Qianrong [1 ]
Wang, Chengming [1 ]
机构：
[1] Jinan Univ, Dept Chem, Coll Chem & Mat Sci, Guangzhou 511443, Peoples R China
来源：
RSC ADVANCES | 2021年 / 11卷 / 21期
关键词：
39;
D O I：
10.1039/d1ra01779a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A rhodium-catalyzed, N-H free indole directed cyclization reaction of benzoquinone via a dual C-H activation strategy is disclosed. This protocol has a good functional group tolerance and affords useful indole-fused heterocylces. Besides, it is insensitive to moisture, commercially available solvent can be directly used and work quite well for this transformation.
引用
收藏
页码：13030 / 13033
页数：4
相关论文
共 50 条
  • [21] Construction of Highly Functionalized Xanthones via Rh-Catalyzed Cascade C-H Activation/O-Annulation
    Nale, Sagar D.
    Maiti, Debabrata
    Lee, Yong Rok
    ORGANIC LETTERS, 2021, 23 (07) : 2465 - 2470
  • [22] A removable directing group-assisted Rh(iii)-catalyzed direct C-H bond activation/annulation cascade to synthesize highly fused isoquinolines
    Cheng, Yilang
    Han, Xu
    Li, Junyou
    Zhou, Yu
    Liu, Hong
    ORGANIC CHEMISTRY FRONTIERS, 2020, 7 (20): : 3186 - 3192
  • [23] Mild Rhodium(III)-Catalyzed C-H Activation and Intermolecular Annulation with Allenes
    Wang, Honggen
    Glorius, Frank
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 51 (29) : 7318 - 7322
  • [24] Synthesis of indene-fused spiro-dibenz(ox)azepines via Rh(iii)-catalyzed cascade regioselective C-H activation/annulation
    Naskar, Koushik
    Karmakar, Sudip
    Mondal, Imtiaj
    Sarkar, Writhabrata
    Roy, Shantonu
    Roy, Anupam
    Deb, Indubhusan
    CHEMICAL COMMUNICATIONS, 2023, 59 (50) : 7751 - 7754
  • [25] Rh(III)-Catalyzed Trifluoromethylthiolation of Indoles via C-H Activation
    Wang, Qiang
    Xie, Fang
    Li, Xingwei
    JOURNAL OF ORGANIC CHEMISTRY, 2015, 80 (16): : 8361 - 8366
  • [26] Rh(III)-catalyzed C-H activation of N-enoxyphthalimides
    Piou, Tiffany
    Rovis, Tomislav
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
  • [27] Rh(iii)-catalyzed sp3/sp2-C-H heteroarylations via cascade C-H activation and cyclization
    Chaturvedi, Atul K.
    Shukla, Rahul K.
    Volla, Chandra M. R.
    CHEMICAL SCIENCE, 2024, 15 (17) : 6544 - 6551
  • [28] Rh(III)-catalyzed C-H activation of benzamides: Coupling with quinones
    Qi, Zisong
    Li, Xingwei
    CHINESE JOURNAL OF CATALYSIS, 2015, 36 (01) : 48 - 56
  • [29] Rh-Catalyzed aldehydic C-H alkynylation and annulation
    Rao, Maddali L. N.
    Ramakrishna, Boddu S.
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2020, 18 (07) : 1402 - 1411
  • [30] Three-Component Synthesis of Isoquinolone Derivatives via Rh(III)-Catalyzed C-H Activation and Tandem Annulation
    Yang, Zhenke
    Liu, Jidan
    Li, Yuting
    Ding, Jiawen
    Zheng, Liyao
    Liu, Zhao-Qing
    JOURNAL OF ORGANIC CHEMISTRY, 2022, 87 (21): : 14809 - 14818
12345