Inhibition of EZH1 and EZH2 Restores Chemosensitivity of Leukemia Stem Cells in Acute Myeloid Leukemia By Recruitment of Quiescent AML Stem/Progenitor Cells

被引:4
|
作者
Chang, Kyung Hee
Alaniz, Zoe
Nishida, Yuki
Dos Santos, Cedric E.
Slosberg, Eric
Daver, Naval
Andreeff, Michael
机构
关键词
D O I
10.1182/blood-2020-142071
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [41] Inhibition of the Mitochondrial Protein Import Machinery Is Selectively Cytotoxic to Acute Myeloid Leukemia (AML) Cells and Stem Cells
    Jeyaraju, Danny V.
    Voisin, Veronique
    Xu, Changjiang
    Hurren, Rose
    Gronda, Marcela
    Wang, Xiaoming
    Jitkova, Yulia
    Soriano, Joelle
    MacLean, Neil
    Bader, Gary D.
    Schimmer, Aaron D.
    BLOOD, 2016, 128 (22)
  • [42] Acute Myeloid Leukemia Stem Cells Cells Are Rare and Heterogeneous in Human Acute Myeloid Leukemia
    Sarry, Jean-Emmanuel
    Murphy, Kathleen
    Danet-Desnoyers, Gwenn-Ael
    Carroll, Martin
    BLOOD, 2009, 114 (22) : 162 - 163
  • [43] Cell adhesion-induced phosphorylation and inactivation of EZH2 confer drug resistance to acute myeloid leukemia cells
    Kikuchi, Jiro
    Kuroda, Yoshiaki
    Koyama, Daisuke
    Furukawa, Yusuke
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 2018, 107 (03) : 383 - 385
  • [44] Cell adhesion-induced phosphorylation and inactivation of EZH2 confer drug resistance to acute myeloid leukemia cells
    Jiro Kikuchi
    Yoshiaki Kuroda
    Daisuke Koyama
    Yusuke Furukawa
    International Journal of Hematology, 2018, 107 : 383 - 385
  • [45] Human acute myeloid leukemia stem cells
    Hope, KJ
    Jin, LQ
    Dick, JE
    ARCHIVES OF MEDICAL RESEARCH, 2003, 34 (06) : 507 - 514
  • [46] Targeting the Acute Myeloid Leukemia Stem Cells
    Krause, Alexandre
    Fontanari Krause, Luciana M.
    Rego, Eduardo M.
    ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2010, 10 (02) : 104 - 110
  • [47] Leukemic stem cells in acute myeloid leukemia
    Buske, C.
    ONKOLOGIE, 2012, 35 : 171 - 171
  • [48] Therapeutic targeting of leukemia stem cells in acute myeloid leukemia
    Barbosa, Karina
    Deshpande, Aniruddha J.
    FRONTIERS IN ONCOLOGY, 2023, 13
  • [49] Epigenetic Abnormalities in Acute Myeloid Leukemia and Leukemia Stem Cells
    Xu, Jing
    Hang, Xiaohang
    Wu, Baohong
    Chen, Chong
    Liu, Yu
    LEUKEMIA STEM CELLS IN HEMATOLOGIC MALIGNANCIES, 2019, 1143 : 173 - 189
  • [50] Therapeutic inhibition of PPARα-HIF1α-PGK1 signaling targets leukemia stem and progenitor cells in acute myeloid leukemia
    Zhou, Hui
    Jiang, Yuelong
    Huang, Yuetin
    Zhong, Mengya
    Qin, Dongmei
    Xie, Chendi
    Pan, Guangchao
    Tan, Jinshui
    Deng, Manman
    Zhao, Haijun
    Zhou, Yong
    Tang, Yuanfang
    Lai, Qian
    Fang, Zhihong
    Luo, Yiming
    Jiang, Yirong
    Xu, Bing
    Zha, Jie
    CANCER LETTERS, 2023, 554