Cooperation of MT1-MMP and LOX-1 for RhoA- and Rac1-dependent Signaling Pathways in Oxidized LDL-mediated Endothelial Dysfunction and Atherosclerosis

被引：0
|
作者：
Sugimoto, Koichi [1 ]
Ishibashi, Toshiyuki [1 ]
Sawamura, Tatsuya [2 ]
Uekita, Hironori [1 ]
Kamioka, Masashi [1 ]
Inoue, Nobutaka [2 ]
Shiomi, Masashi [3 ]
Takuwa, Yoh [4 ]
Teramoto, Tamio [5 ]
Takeishi, Yasuchika [1 ]
机构：
[1] Fukushima Med Univ, Dept Cardiol & Hematol, Fukushima, Japan
[2] Natl Cardiovasc Ctr, Res Inst, Dept Biosci, Osaka, Japan
[3] Kobe Univ, Sch Med, Inst Expt Anim, Kobe, Hyogo 650, Japan
[4] Kanazawa Univ, Sch Med, Dept Physiol, Kanazawa, Ishikawa 920, Japan
[5] Teikyo Univ, Sch Med, Dept Internal Med, Tokyo 173, Japan
来源：
CIRCULATION | 2009年 / 120卷 / 18期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：S1119 / S1120
页数：2
相关论文
共 34 条
  • [21] Hemoglobin -Mediated Oxidation of Low -Density Lipoprotein (oxLDL) Contributes to Lung Microvascular Endothelial Dysfunction Via Lectin-Like Oxidized LDL Receptor 1 (LOX-1)
    Meegan, Jamie
    Douglas, Joel
    Riedmann, Kyle
    Ware, Lorraine
    Bastarache, Julie
    PHYSIOLOGY, 2024, 39
  • [22] Aspirin decreases oxidized-LDL-mediated upregulation of LOX-1 and interferes with intracellular signaling: A novel mechanism of action of aspirin
    Mehta, JL
    Yu, F
    Li, DY
    CIRCULATION, 2002, 106 (19) : 280 - 281
  • [23] Liraglutide ameliorates oxidized LDL-induced endothelial dysfunction by GLP-1R-dependent downregulation of LOX-1-mediated oxidative stress and inflammation
    Wu, Ying
    Song, Meiyan
    Chen, Wen
    Xu, Kaizu
    Wu, Meifang
    Lin, Liming
    REDOX REPORT, 2023, 28 (01)
  • [24] Resveratrol attenuates oxidized LDL-evoked Lox-1 signaling and consequently protects against apoptotic insults to cerebrovascular endothelial cells
    Chang, Huai-Chia
    Chen, Tyng-Guey
    Tai, Yu-Ting
    Chen, Ta-Liang
    Chiu, Wen-Ta
    Chen, Ruei-Ming
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2011, 31 (03): : 842 - 854
  • [25] LOX-1, an oxidized LDL endothelial receptor, induces CD40/CD401 signaling in human coronary artery endothelial cells
    Liu, L
    Li, DY
    Remeo, F
    Sawamura, T
    Mehta, JL
    CIRCULATION, 2001, 104 (17) : 172 - 172
  • [26] Hemoglobin-mediated Oxidation of Low-density Lipoprotein (oxLDL) Contributes to Lung Microvascular Endothelial Dysfunction Via Lectin-like Oxidized LDL Receptor 1 (LOX-1)
    Meegan, J. E.
    Douglas, J. S.
    Riedmann, K. J.
    Ware, L. B.
    Bastarache, J. A.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2024, 209
  • [27] LOX-1, an oxidized LDL endothelial receptor, induces CD40/CD40L signaling in human coronary artery endothelial cells
    Li, DY
    Liu, L
    Chen, HJ
    Sawamura, T
    Mehta, JL
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2003, 23 (05) : 816 - 821
  • [28] MT1-MMP Controls Akt-Dependent Fox01 Activation in TNF-alpha-Induced Signaling Pathways of Endothelial Cell Apoptosis and Haemostasis
    Ohkawara, Hiroshi
    Ishibashi, Toshiyuki
    Ando, Katuya
    Sugimoto, Koichi
    Sakamoto, Nobuo
    Uekita, Hironori
    Takeishi, Yasuchika
    CIRCULATION, 2010, 122 (21)
  • [29] Dihydrotanshinone I Attenuates Atherosclerosis in ApoE-Deficient Mice: Role of NOX4/NF-κB Mediated Lectin-Like Oxidized LDL Receptor-1 (LOX-1) of the Endothelium
    Zhao, Wenwen
    Li, Chunxia
    Gao, Hongwei
    Wu, Qin
    Shi, Jingshan
    Chen, Xiuping
    FRONTIERS IN PHARMACOLOGY, 2016, 7
  • [30] RANKL initiates a Src-dependent signaling pathway inducing prostate cancer cell migration mediated by tumor-derived MT1-MMP activity
    Sabbota, Aaron L.
    Dong, Zhong
    Bonfil, R. Daniel
    Chinni, Sreenivasa R.
    Nabha, Sanna M.
    Cher, Michael L.
    CLINICAL & EXPERIMENTAL METASTASIS, 2009, 26 (07) : 915 - 916
1234