Outcomes of patients with haematological malignancies admitted to intensive care unit. A comparative review of allogeneic haematopoietic stem cell transplantation data

被引：22
|
作者：
Lim, ZiYi
Pagliuca, Antonio
Simpson, Sylwia
Cottam, Simon
Ervine, Max
Ho, Aloysius Y. L.
Devereux, Stephen
Mufti, Ghulam J.
机构：
[1] Kings Coll Hosp London, Dept Haematol Med, London SE5 9RS, England
[2] Kings Coll London, London WC2R 2LS, England
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 2007年 / 136卷 / 03期
关键词：
intensive care; haematological malignancies; allogeneic stem cell transplantation; reduced intensity conditioning;
D O I：
10.1111/j.1365-2141.2006.06440.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The outcomes of 55 consecutive haemato-oncology patients admitted to the intensive care unit (ICU) were retrospectively analysed. Twenty-eight patients were admitted following haemopoietic stem cell transplantation (HSCT). Thirty-nine patients were admitted with respiratory failure, and all patients required respiratory support. Seventeen patients survived to be discharged from ICU, with an actuarial 1-year survival of 18%. Overall survival between patients who received intensive chemotherapy and those who underwent allogeneic HSCT was not significantly different (19% vs. 10%, P = 0.19). None of the nine myeloablative HSCT recipients survived (median survival: 9 d). Six of the 15 reduced-intensity conditioned HSCT recipients survived beyond 1 year (median survival: 1050 d, range: 438-1437).
引用
收藏
页码：448 / 450
页数：3
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