MgO Nanoparticles as a Recyclable Heterogeneous Catalyst for the Synthesis of Polyhydroquinoline Derivatives under Solvent Free Conditions

被引:18
|
作者
Ranjbar-Karimi, Reza [1 ]
Hashemi-Uderji, Somayeh [1 ]
Bazmandegan-Shamili, Alireza [1 ]
机构
[1] Vali E Asr Univ, Fac Sci, Dept Chem, Rafsanjan, Iran
关键词
multicomponent reaction; cyclization; nanoparticle; magnesium oxide; polyhydroquinoline; dihydropyridines; aldehyde; ONE-POT SYNTHESIS; CALCIUM-ANTAGONISM; 1,4-DIHYDROPYRIDINES;
D O I
10.1002/cjoc.201180291
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Magnesium oxide nanopartticels in average size between 35-120 nm were prepared by sonochemistry method. Synthesis of polyhydroquinoline derivatives using MgO nanoparticles from the reaction of dimedone, benzaldehyde, ethyl acetoacetate and ammonium acetate under solvent-free conditions is reported. Easy handling, reusability, thermal stability and non-toxicity of the catalyst make the present protocol as an eco-friendly and economically acceptable method for synthesis of these heterocycles.
引用
收藏
页码:1624 / 1628
页数:5
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