BCR-ABL1 negative chronic myeloid leukemia: report of two cases

被引：0

作者：

Figueroa-Faundez, Fernanda ^{[1
]}

Vidal-Rojas, Catalina ^{[1
]}

Briones-Munoz, Vania ^{[1
]}

Chandia-Cabas, Mauricio ^{[1
,2
]}

机构：

[1] Univ Concepcion, Fac Med, Dept Med, Concepcion, Chile

[2] Hosp Guillermo Grant Benavente, Serv Hematol, Concepcion 1436, Chile

来源：

REVISTA MEDICA DE CHILE | 2022年 / 150卷 / 03期

关键词：

Disseminated Intravascular Coagulation; Flow Cytometry; Chile; Leukemia; Myeloid; Chronic; Atypical; BCR-ABL Negative;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

BCR-ABL1 negative atypical chronic myeloid leukemia (aCML) is a rare type of myeloproliferative / myelodysplastic syndrome characterized by leukocytosis and proliferation of dysplastic neutrophilic precursors in the absence of positivity for the BCR-ABL1 fusion gene. We report a 66-year-old woman and a 57-year-old man with aCML, who initially presented with general malaise and weight loss, associated with anemia, thrombocytopenia, and leukocytosis with left shift and dysplasia in the neutrophil series. Both evolved unfavorably after admission and died a few days later due to multiple organ failure.

引用

页码：397 / 401

页数：5

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