Enantiomeric resolution and determination of the absolute configuration of dibenzophosphole 5-oxides

被引：33
|
作者：
Durán, E
Gordo, E
Granell, J
Font-Bardía, M
Solans, X
Velasco, D
López-Calahorra, F
机构：
[1] Univ Barcelona, Dept Quim Organ, E-08028 Barcelona, Spain
[2] Univ Barcelona, Dept Quim Inorgan, E-08028 Barcelona, Spain
[3] Univ Barcelona, Dept Cristallog & Diposits Minerals, E-08028 Barcelona, Spain
来源：
TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 14期
关键词：
D O I：
10.1016/S0957-4166(01)00339-1
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The resolution of asymmetrically substituted dibenzophospholes via chromatographic separation of their cyclopalladium derivatives is described for the first time. The absolute configuration of the phosphorus atom was determined by X-ray crystallographic analysis in one case. A general NMR criterion for the complete determination of the configuration of this group of products is proposed. The enantiomeric excess of the resolved compounds was determined by NMR Eu(III) chemical displacement experiments and by HPLC using a chiral stationary phase. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：1987 / 1997
页数：11
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