3-Butyl-2-morpholino-5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidin-4(3H)-one

被引:0
|
作者
Zeng, Xiao-Hua [1 ]
Wang, Hong-Mei [1 ]
Zheng, Ai-Hua [1 ]
Tian, Jia-Hua [1 ]
He, Ting-Yun [1 ]
机构
[1] Yunyang Med Coll, Dept Med Chem, Shiyan 442000, Peoples R China
关键词
D O I
10.1107/S1600536807057558
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
In the title molecule, C18H25N3O2S, the central thienopyrimidine ring system is essentially planar. The cyclohexene ring, in which the four CH2 groups are disordered in an approximately 1:1 ratio, adopts a half-chair conformation, while the morpholine ring is in a standard chair conformation. The butyl group is disordered in an approximately 2: 1 ratio. In the crystal structure, weak intermolecular C-H center dot center dot center dot O hydrogen-bonding interactions stabilize the crystal structure.
引用
收藏
页码:O4840 / U6279
页数:13
相关论文
共 50 条
  • [31] Reactions of 2-(2-propynylsulfanyl)-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-d]pyrimidin-4(3H)-one with arylsulfenyl chlorides
    A. I. Vas’kevich
    R. I. Vas’kevich
    V. I. Staninets
    S. A. But
    A. N. Chernega
    Russian Journal of Organic Chemistry, 2007, 43 : 1526 - 1531
  • [32] Synthesis of some new bioactive 3-amino-2-mercapto-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one derivatives
    Ashalatha, B. V.
    Narayana, B.
    Raj, K. K. Vijaya
    Kumari, N. Suchetha
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2007, 42 (05) : 719 - 728
  • [33] 7-Benzyl-3-(4-fluorophenyl)-2-propyl-amino-5,6,7,8-tetrahydropyrido-[4 ',3 ':4,5]thieno[2,3-d]pyrimidin-4(3H)-one
    Hu, Hai-Jun
    Chen, Hong
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O1097 - +
  • [34] New efficient synthesis of 2-substituted 5,6,7,8-tetrahydro-benzothieno[2,3-d]pyrimidin-4(3H)-ones
    Ding, MW
    Yang, SJ
    Zhu, J
    SYNTHESIS-STUTTGART, 2004, (01): : 75 - 79
  • [35] Efficient synthesis of furo[2,3-d]pyrimidin-4(3H)-ones
    Hu, Yang-Gen
    Li, Gui-Hua
    Ding, Ming-Wu
    ARKIVOC, 2008, : 151 - 158
  • [36] Synthesis and Characterization of New 2-Methoxy-thieno[2,3-d]pyrimidin-4(3H)-one
    Lu, Lian-Ying
    Yu, Zhong-Shan
    Fang, Zheng-Dong
    Chen, Yong-Zhou
    Zhou, Wen
    Wei, Xian-Hong
    Tao, Qing
    ADVANCES IN CHEMICAL ENGINEERING II, PTS 1-4, 2012, 550-553 : 89 - 92
  • [37] Synthesis of Novel Substituted 2-Lactosylthiothieno[2,3-d]pyrimidin-4 (3H)-one Derivatives
    Dai, Qiu-hong
    Yan, Kai
    Liu, Ming-guo
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 51 (05) : 1390 - 1394
  • [38] Synthesis of some new 2-arylthieno[2,3-d]pyrimidin-4(3H)-one derivatives
    Davoodnia, Abolghasem
    Eshghi, Hossein
    Salavaty, Akrarn
    Tavakoli-Hoseini, Niloofar
    JOURNAL OF CHEMICAL RESEARCH, 2008, (01) : 1 - 2
  • [39] Derivatives of the condensed thieno[2,3-d]pyrimidines.: 20.: Synthesis of 2-substituted 5,6-dihydro-8H-pyrano[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-ones and 5,6,7,8-tetrahydrobenzo[b]thieno[2,3-d]pyrimidin-4(3H)-ones
    Mkrtchyan, AP
    Noravyan, AS
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 2006, (03): : 441 - 444
  • [40] Synthesis of 2-amino-thieno[2,3-d]pyrimidin-4(3H)-ones
    Hu, YG
    Lu, MY
    Song, HL
    Ding, MW
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2005, 25 (03) : 295 - 298