Randomised controlled trial of a reduced-visits programme of antenatal care in Harare, Zimbabwe

被引:102
|
作者
Munjanja, SP
Lindmark, G
Nystrom, L
机构
[1] UNIV UPPSALA,DEPT OBSTET & GYNAECOL,UPPSALA,SWEDEN
[2] UMEA UNIV,DEPT EPIDEMIOL & PUBL HLTH,UMEA,SWEDEN
来源
LANCET | 1996年 / 348卷 / 9024期
关键词
D O I
10.1016/S0140-6736(96)01250-0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background Many of the individual components of antenatal care have been studied in randomised controlled trials, but few studies have compared whole programmes of antenatal care. Our aim was to test the hypothesis that a new programme of antenatal care with fewer goal-oriented visits would give an equivalent or better result in the outcomes associated with pregnancy and delivery. Methods In a randomised clinical trial in Harare, Zimbabwe, we compared a new programme of antenatal care with the standard programme. The new programme consisted of fewer but more objectively oriented procedures per visit. Seven primary randomly assigned to the two programmes-three to the standard programme and four to the new programme. Findings Over a 2-year period, 15 994 women were recruited into the study at the time they booked antenatal cave, 97% of the women were followed up, 9394 who had followed the new programme, and 6138 from clinics with the standard one, Women allocated to the new programme made, as planned, fewer visits than those in the standard programme (median 4 vs 6 visits, respectively). The proportion of antenatal referrals was also lower (13.6 vs 15.3%: odds ratio 0.87 [95% CI 0.79-0.95]) because of fewer referrals for pregnancy-induced (2.5 vs 3.8%; 0.66 [0.55-0.79]). Nevertheless, there were significantly fewer labour referrals for severe hypertension or eclampsia (2.1 vs 2.6%; 0.81 [0.66-1.00]). The risk for preterm (<37 weeks) delivery was significantly lower for women on the new programme (10.1 vs 11.5%: 0.86 [0.78-0.96]). There were no other significant differences between the programmes in other major indices of pregnancy outcome, including antenatal referrals for other causes, labour referrals, obstetric interventions, low birthweight, and perinatal and maternal mortality and morbidity. Interpretation An antenatal care programme with fewer more objectively oriented visits can be introduced without adverse effects on the main intermediate outcome pregnancy variables.
引用
收藏
页码:364 / 369
页数:6
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