Absence of Epstein-Barr virus in esophageal squamous cell carcinoma

被引：14
|
作者：
Sunpaweravong, S [1 ]
Mitarnun, W
Puttawibul, P
机构：
[1] Prince Songkla Univ, Songklanagarind Hosp, Dept Surg, Hat Yai 90110, Thailand
[2] Prince Songkla Univ, Songklanagarind Hosp, Dept Pathol, Hat Yai 90110, Thailand
来源：
DISEASES OF THE ESOPHAGUS | 2005年 / 18卷 / 06期
关键词：
Epstein-Barr virus; esophageal squamous cell carcinoma; etiology;
D O I：
10.1111/j.1442-2050.2005.00522.x
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
It is strongly suspected that the Epstein-Barr virus (EBV) plays a role in the genesis of nasopharyngeal and gastric carcinoma. The aim of this study was to search for such a connection between esophageal squamous cell carcinoma (ESCC) and EBV. We investigated 104 surgically resected esophageal cancers using in situ hybridization (ISH) for EBV-encoded RNA (EBER). We found no EBER-positive cancer cells in any tests, although there were five samples in which EBER-positive tumor-infiltrating lymphocytes (TILs) were found. We conclude from this study that EBV is not associated with ESCC.
引用
收藏
页码：398 / 399
页数：2
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