Plasma Neutralization of the SARS-CoV-2 Omicron Variant

被引：305
|
作者：
Schmidt, Fabian [1 ]
Muecksch, Frauke [1 ]
Weisblum, Yiska [1 ]
Da Silva, Justin [1 ]
Bednarski, Eva [1 ]
Cho, Alice [1 ]
Wang, Zijun [1 ]
Gaebler, Christian [1 ]
Caskey, Marina [1 ]
Nussenzweig, Michel C. [1 ]
Hatziioannou, Theodora [1 ]
Bieniasz, Paul D. [1 ]
机构：
[1] Rockefeller Univ, 1230 York Ave, New York, NY 10021 USA
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2022年 / 386卷 / 06期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1056/NEJMc2119641
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Omicron Neutralization after the Third Vaccine Dose Neutralization assays of SARS-CoV-2 pseudoviruses expressing wild-type, omicron, or a synthetic resistant spike protein in plasma drawn from 47 people over time showed much lower omicron neutralization than Wuhan-hu-1 neutralization after two doses of an mRNA vaccine. However, samples from persons vaccinated after recovery from Covid-19 and those who received a booster vaccine had high levels of omicron neutralization.
引用
收藏
页码：599 / 601
页数：4
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