Biaryl Formation via Base-Promoted Direct Coupling Reactions of Arenes with Aryl Halides

被引：10

作者：

Iqbal, Muhammad Asif ^{[1
]}

Lu, Le ^{[1
]}

Mehmood, Hina ^{[1
]}

Hua, Ruimao ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China

来源：

ACS OMEGA | 2021年 / 6卷 / 24期

基金：

中国国家自然科学基金;

关键词：

C-H ARYLATION; BOND FORMATION;

D O I：

10.1021/acsomega.1c01736

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the absence of ligand, Cs2CO3-promoted cross-coupling reaction of arenes with cyano-/nitro-substituted aryl halides in DMSO affording biaryls is reported. The cyano/nitro group in biaryls is useful and convenient for further transformation. The formation of dibenzofurans resulting from the reactions between arenes and 1-bromo-2-iodobenzene is also reported. On the basis of control experiments and theoretical studies, a radical mechanism is proposed for the formation of biaryls.

引用

页码：15981 / 15987

页数：7

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