Ytterbium Triflate Promoted One-Pot Three Component Synthesis of 3,4,5-Trisubstituted-3,6-dihydro-2H-1,3-oxazines

被引：13
|
作者：
Epifano, Francesco [2 ]
Pelucchini, Caroline [1 ]
Rosati, Ornelio [1 ]
Genovese, Salvatore [2 ]
Curini, Massimo [1 ]
机构：
[1] Univ Perugia, Dipartimento Chim & Tecnol Farmaco, Sez Chim Organ, I-06123 Perugia, Italy
[2] Univ G dAnnunzio, Dipartimento Sci Farmaco, I-66100 Chieti, CH, Italy
来源：
CATALYSIS LETTERS | 2011年 / 141卷 / 06期
关键词：
Heterogeneous catalysis; Multicomponent reactions; Lanthanides; Oxazine derivatives; Ytterbium triflate; MULTICOMPONENT REACTIONS; 3-COMPONENT SYNTHESIS; DOMINO REACTIONS; CHEMISTRY; BOND;
D O I：
10.1007/s10562-011-0605-3
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
An efficient one-pot synthesis of 3,4,5-trisubstituted-3,6-dihydro-2H-1,3-oxazines from acetylene dicarboxylates, aromatic and aliphatic amines, and formaldehyde is described. The six member N,O-heterocyclic nucleus was constructed via Yb(OTf)(3) promoted domino hydroamination/Prins reaction/cyclization/dehydration reactions.
引用
收藏
页码：844 / 849
页数：6
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