Mixed apocrine/endocrine ductal carcinoma in situ of the breast coexistent with lobular carcinoma in situ

被引：5
|
作者：
Coyne, JD
Dervan, PA
Barr, L
Baildam, AD
机构：
[1] Univ S Manchester Hosp, NHS Trust, Withington Hosp, Dept Pathol, Manchester M20 2LR, Lancs, England
[2] Withington Hosp, Dept Surg, Manchester, Lancs, England
[3] Mater Hosp, Dept Pathol, Dublin 7, Ireland
来源：
JOURNAL OF CLINICAL PATHOLOGY | 2001年 / 54卷 / 01期
关键词：
lobular carcinoma in situ; ductal carcinoma in situ; apocrine differentiation;
D O I：
10.1136/jcp.54.1.70
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
An unusual mixed form of ductal carcinoma in situ (DCIS) of the breast is described, which exhibits a biphenotypic morphology encompassing a range of differential diagnostic DCIS subtypes. In adddition, immunophenotypic and ultrastructural studies demonstrate neuroendocrine and apocrine differentiation, raising questions regarding appropriate classification and biological behaviour. In two cases, coexistence of this mixed form of DCIS with lobular carcinoma in situ (LCIS) in the same duct lobular units is an additional unusual feature that might, at least in some cases, indicate a closer relation between them.
引用
收藏
页码：70 / 73
页数：4
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