Smart sensor systems for human health breath monitoring applications

被引:30
|
作者
Hunter, G. W. [1 ]
Xu, J. C. [1 ]
Biaggi-Labiosa, A. M. [1 ]
Laskowski, D. [2 ]
Dutta, P. K. [3 ]
Mondal, S. P. [3 ]
Ward, B. J. [4 ]
Makel, D. B. [4 ]
Liu, C. C. [5 ]
Chang, C. W. [6 ]
Dweik, R. A. [2 ]
机构
[1] NASA Glenn Res Ctr, Cleveland, OH 44135 USA
[2] Cleveland Clin, Cleveland, OH 44106 USA
[3] Ohio State Univ, Dept Chem, Columbus, OH 43210 USA
[4] Makel Engn Inc, Cleveland, OH USA
[5] Case Western Reserve Univ, Cleveland, OH 44106 USA
[6] ASRC Aerosp NASA Glenn Res Ctr, Cleveland, OH USA
关键词
EXHALED NITRIC-OXIDE; LEUKOTRIENE B-4; SPECTROMETRY ANALYSIS; LUNG-FUNCTION; VALIDATION; DIAGNOSIS; 8-ISOPROSTANE; CHILDREN; CANCER; ASTHMA;
D O I
10.1088/1752-7155/5/3/037111
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Breath analysis techniques offer a potential revolution in health care diagnostics, especially if these techniques can be brought into standard use in the clinic and at home. The advent of microsensors combined with smart sensor system technology enables a new generation of sensor systems with significantly enhanced capabilities and minimal size, weight and power consumption. This paper discusses the microsensor/smart sensor system approach and provides a summary of efforts to migrate this technology into human health breath monitoring applications. First, the basic capability of this approach to measure exhaled breath associated with exercise physiology is demonstrated. Building from this foundation, the development of a system for a portable asthma home health care system is described. A solid-state nitric oxide (NO) sensor for asthma monitoring has been identified, and efforts are underway to miniaturize this NO sensor technology and integrate it into a smart sensor system. It is concluded that base platform microsensor technology combined with smart sensor systems can address the needs of a range of breath monitoring applications and enable new capabilities for healthcare.
引用
收藏
页数:11
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