Talking to patients about biosimilars

被引:16
|
作者
Janjigian, Yelena Y. [1 ,2 ]
Bissig, Marco [3 ]
Curigliano, Giuseppe [4 ,5 ]
Coppola, Jennifer [6 ]
Latymer, Mark [7 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Gastrointestinal Oncol Serv, New York, NY 10065 USA
[2] Weill Cornell Med Coll, New York, NY 10065 USA
[3] ISFSI, Serv Cent Farm, Lugano, Switzerland
[4] Univ Milan, European Inst Oncol, Div Early Drug Dev, Milan, Italy
[5] Univ Milan, Dept Hematol Oncol, Milan, Italy
[6] Pfizer Inc, New York, NY 10017 USA
[7] Pfizer Ltd, Sandwich, Kent, England
关键词
biosimilar; healthcare provider; patient access; patient communication; regulatory pathway; totality of evidence; INFLAMMATORY-BOWEL-DISEASE; BREAST-CANCER; CLINICAL CONSIDERATIONS; BIOLOGICAL THERAPIES; PHYSICIAN SURVEY; UNITED-STATES; IMPACT; ONCOLOGY; SAFETY; INFLIXIMAB;
D O I
10.2217/fon-2018-0044
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Biologic therapies target aberrant pathways in diseases including diabetes, cancer and autoimmune disorders. Despite recent scientific advances, patient access to these agents can be limited. Biosimilars are designed to be highly similar to the originator biologic, targeting the same biological pathways, with comparable efficacy and safety. Biosimilars have the advantage of lower treatment costs, offering the potential for increased clinical use and patient access. Several biosimilars are approved for clinical use in the USA and Europe; however, there is a lack of awareness about biosimilars among healthcare providers and patients. This overview of the scientific basis of biosimilars and current indications aim to enhance discussions with patients and increase understanding of the role of biosimilars in individual treatment plans.
引用
收藏
页码:2403 / 2414
页数:12
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