Bioinspired Strong and Highly Porous Glass Scaffolds

被引:185
|
作者
Fu, Qiang [1 ]
Saiz, Eduardo [2 ]
Tomsia, Antoni P. [1 ]
机构
[1] Univ Calif Berkeley, Lawrence Berkeley Lab, Div Mat Sci, Berkeley, CA 94720 USA
[2] Univ London Imperial Coll Sci Technol & Med, Dept Mat, Ctr Adv Struct Ceram, London, England
基金
英国工程与自然科学研究理事会; 美国国家卫生研究院;
关键词
IN-VITRO PERFORMANCE; CERAMIC SCAFFOLDS; PHOSPHATE SCAFFOLDS; FABRICATION; COATINGS; DESIGN; BIOGLASS(R); SURFACE;
D O I
10.1002/adfm.201002030
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The quest for more efficient energy-related technologies is driving the development of porous and high-performance structural materials with exceptional mechanical strength. Natural materials achieve their strength through complex hierarchical designs and anisotropic structures that are extremely difficult to replicate synthetically. We emulate nature's design by direct-ink-write assembling of glass scaffolds with a periodic pattern, and controlled sintering of the filaments into anisotropic constructs similar to biological materials. The final product is a porous glass scaffold with a compressive strength (136 MPa) comparable to that of cortical bone and a porosity (60%) comparable to that of trabecular bone. The strength of this porous glass scaffold is similar to 100 times that of polymer scaffolds and 4-5 times that of ceramic and glass scaffolds with comparable porosities reported elsewhere. The ability to create both porous and strong structures opens a new avenue for fabricating scaffolds for a broad array of applications, including tissue engineering, filtration, lightweight composites, and catalyst support.
引用
收藏
页码:1058 / 1063
页数:6
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