ACQUIRED HEMOPHILIA A

被引：20
|
作者：
Franchini, Massimo [1 ]
Lippi, Giuseppe [2 ]
机构：
[1] Univ Hosp Parma, Dept Pathol & Lab Med, Immunohematol & Transfus Ctr, Parma, Italy
[2] Univ Hosp Parma, Clin Chem Lab, Dept Pathol & Lab Med, Parma, Italy
来源：
ADVANCES IN CLINICAL CHEMISTRY, VOL 54 | 2011年 / 54卷
关键词：
FACTOR-VIII; ANTIBODIES; RITUXIMAB; INACTIVATION; INHIBITORS; PROGNOSIS; DIAGNOSIS; KINETICS; BINDING; IGG;
D O I：
10.1016/B978-0-12-387025-4.00003-0
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Acquired hemophilia A is a rare but often life-threatening hemorrhagic disorder characterized by an autoantibody directed against coagulation factor VIII. Fifty per cent of cases are idiopathic whereas the remaining 50% are associated with pregnancy, autoimmune conditions, malignancies and drugs. In this review the actual knowledge on diagnostic and therapeutic aspects of this disease will be summarized.
引用
收藏
页码：71 / 80
页数：10
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