Indications and outcomes of phototherapeutic keratectomy in the developing world

Purpose: To analyze the indications and outcomes of phototherapeutic keratectomy (PTK) in the developing world. Methods: In this retrospective study, the records of 203 consecutive eyes of 191 patients who had undergone PTK at a tertiary eye care center were evaluated. The parameters assessed were indications of PTK, demographic features, best spectacle-corrected visual acuity (BSCVA), and pachymetry. PTK was done by using a 193-nm Ar-F Excimer laser (Chiron Technolas Keracor 217 C) in a 6-mm optic zone. Patients were followed up for 6 months. Results: The most common indication of PTK was symptomatic bullous keratopathy (103 eyes). The patients were divided into 2 groups: those with bullous keratopathy (PTK BK) and those with superficial corneal pathologies (PTK CS). In the PTK CS group, the most common indications were Salzmann nodular degeneration (n = 27) and spheroidal degeneration (n = 22). BSCVA improved from 20/222 (0.09) to 20/86 (0.23) in the PTK CS group and 20/384 (0.05) to 20/202 (0.09) in the PTK BK group (P < 0.0001 in both groups). There was a significant decrease in the number of patients with severe symptoms in the PTK-BK (P < 0.0001) and PTK-CS (P = 0.017) groups. The change in BSCVA was significantly related to both pre-PTK BSCVA and pachymetry in PTK-BK. Conclusions: PTK is an efficacious treatment modality for symptomatic relief and visual gain in cases with superficial corneal involvement and bullous keratopathy.