Cognitive profiles in persons with chronic schizophrenia

被引：24
|
作者：
Dawes, Sharron E. [1 ]
Jeste, Dilip V. [1 ]
Palmer, Barton W. [1 ]
机构：
[1] Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA
来源：
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY | 2011年 / 33卷 / 08期
关键词：
Psychosis; Neurocognitive; Factor analysis; Heterogeneity; Idiographic; DECISIONAL CAPACITY; 6-FACTOR MODEL; OLDER PATIENTS; DEFICITS; MEMORY; HETEROGENEITY; IMPAIRMENT; DISORDERS;
D O I：
10.1080/13803395.2011.578569
中图分类号：
B849 [应用心理学];
学科分类号：
040203 ;
摘要：
Cognitive heterogeneity has been a key barrier to clarifying the neuropathologic underpinnings of schizophrenia. We used an idiographic method for cluster analysis of neuropsychological data from 144 middle-aged and older people with schizophrenia to characterize and group the patterns of relative (within-person) profiles of cognitive strength and weakness. Results indicated a 5-cluster solution as most appropriate, with relatively even distribution across the 5 clusters in terms of the proportion of patients in each cluster. Cognitive subtyping may be useful in imaging and genetic research on schizophrenia, as well as having practical utility in treatment planning and cognitive rehabilitation.
引用
收藏
页码：929 / 936
页数：8
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