Synthesizing a nanoparticle distribution in magnetic fluid hyperthermia

被引：7

作者：

Di Barba, P. ^{[1
]}

Dughiero, F. ^{[2
]}

Sieni, E. ^{[2
]}

机构：

[1] Univ Pavia, Dept Elect Engn, I-27100 Pavia, Italy

[2] Univ Padua, Dept Elect Engn, Padua, Italy

来源：

COMPEL-THE INTERNATIONAL JOURNAL FOR COMPUTATION AND MATHEMATICS IN ELECTRICAL AND ELECTRONIC ENGINEERING | 2011年 / 30卷 / 05期

关键词：

Evolutionary computing; Magnetic nanoparticles; FE three-dimensional transient analysis; Nanotechnology; Magnetohydrodynamics; TISSUE; FIELD;

D O I：

10.1108/03321641111152667

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

Purpose - The purpose of this paper is to present the synthesis of magnetic fluid characteristics, like diameter of nanoparficles (NPs) and their concentration, in order to obtain a prescribed temperature rate. An evolution strategy algorithm is used in the optimization procedure, while three-dimensional finite-element (FE) modelling is used for magnetic field and thermal field analysis in transient conditions. Design/methodology/approach - FE analysis has been used in order to compute the magnetic and thermal field in a suitable model of the tumor region. The power density due to NP has been accordingly derived. Findings - The NP distribution, giving a prescribed thermal response, is synthesized. Practical implications The proposed method can be used to design a therapeutic treatment based on magnetic fluid hyperthermia. Originality/value - The paper belongs to a streamline of innovative studies on computational hyperthermia.

引用

页码：1507 / 1516

页数：10

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