A Systematic Analysis of Metal and Metalloid Concentrations in Eight Zebrafish Recirculating Water Systems

被引:1
|
作者
Langa, Xavier [1 ]
Neuhaus, Patrick [2 ]
Lains, David [3 ]
Stewart, Theodora J. [4 ,5 ]
Borel, Nadine [6 ]
Certal, Ana C. [7 ]
Monteiro, Joana F. [7 ]
Alestrom, Peter [8 ]
Diaz, Eduardo [9 ]
Piragyte, Indre [1 ]
Brautigam, Lars [10 ]
Vazquez, Rodolfo
Hlushchuk, Ruslan [11 ]
Gfeller, Lorenz [2 ]
Mestrot, Adrien [2 ]
Bigalke, Moritz [2 ]
Varga, Zoltan M. [3 ]
Mercader, Nadia [1 ]
机构
[1] Univ Bern, Inst Anat & Inst Geog, Div Dev Biol & Regenerat, Baltzerstr 2, CH-3012 Bern, Switzerland
[2] Univ Bern, Inst Geog, Lab Soil Sci, Bern, Switzerland
[3] Univ Oregon, Zebrafish Int Resource Ctr, Eugene, OR USA
[4] Kings Coll London, London Metall Facil, London, England
[5] Imperial Coll London, London, England
[6] Karlsruhe Inst Technol, European Zebrafish Resource Ctr, Eggenstein Leopoldshafen, Germany
[7] Champalimaud Ctr Unknown, Fish Platform, Lisbon, Portugal
[8] Norwegian Univ Life Sci NMBU, Fac Vet Med & Biosci, Dept Basic Sci & Aquat Med, Oslo, Norway
[9] Ctr Nacl Invest Cardiovasculares CNIC, Madrid, Spain
[10] Karolinska Inst, Zebrafish Core Facil, Comparat Med, Stockholm, Sweden
[11] Univ Bern, Inst Anat, Div MicroCT, Bern, Switzerland
基金
欧洲研究理事会;
关键词
aquatic models; animal welfare; environment; metal requirement; metal toxicity; fish nutrition; reproducibility; standards; water quality; zebrafish husbandry; HEAVY-METALS; FUNCTIONAL-DEVELOPMENT; EMBRYONIC-DEVELOPMENT; MAHARLU LAKE; DANIO-RERIO; FISH; TOXICITY; ALUMINUM; CADMIUM; COPPER;
D O I
10.1089/zeb.2020.1970
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Metals and metalloids are integral to biological processes and play key roles in physiology and metabolism. Nonetheless, overexposure to some metals or lack of others can lead to serious health consequences. In this study, eight zebrafish facilities collaborated to generate a multielement analysis of their centralized recirculating water systems. We report a first set of average concentrations for 46 elements detected in zebrafish facilities. Our results help to establish an initial baseline for trouble-shooting purposes, and in general for safe ranges of metal concentrations in recirculating water systems, supporting reproducible scientific research outcomes with zebrafish.
引用
收藏
页码:252 / 264
页数:13
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