Combined Hyperspectral and Spectral Domain Optical Coherence Tomography Microscope for Non-invasive Hemodynamic Imaging

被引：1

作者：

Skala, Melissa C. ^{[1
]}

Hendargo, Hansford ^{[1
]}

Fontanella, Andrew ^{[2
]}

Dewhirst, Mark W. ^{[2
]}

Izatt, Joseph A. ^{[1
]}

机构：

[1] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA

[2] Duke Univ, Dept Radiat Oncol, Durham, NC 27710 USA

来源：

OPTICAL TOMOGRAPHY AND SPECTROSCOPY OF TISSUE VIII | 2009年 / 7174卷

关键词：

MICROVASCULATURE; TUMORS; FLOW;

D O I：

10.1117/12.808183

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We have combined hyperspectral imaging with spectral domain optical coherence tomography (SDOCT) to non-invasively image changes in hemoglobin saturation, blood flow, microvessel morphology and sheer rate on the vessel wall with tumor growth. Changes in these hemodynamic variables were measured over 24 hours in dorsal skin fold window chamber tumors. There was a strong correlation between volumetric flow and hemoglobin saturation (rho = 0.89, p = 9 x 10(-6), N = 15), and a moderate correlation between shear rate on the vessel wall and hemoglobin saturation (rho = 0.56, p = 0.03, N=15).

引用

页数：7

共 50 条

[1] Combined hyperspectral and spectral domain optical coherence tomography microscope for noninvasive hemodynamic imaging
Skala, Melissa C.
Fontanella, Andrew
Hendargo, Hansford
Dewhirst, Mark W.
Izatt, Joseph A.
OPTICS LETTERS, 2009, 34 (03) : 289 - 291
[2] Non-invasive Investigations of a Wall Painting using Optical Coherence Tomography and Hyperspectral Imaging
Liang, Haida
Lange, Rebecca
Howard, Helen
Spooner, Jane
O3A: OPTICS FOR ARTS, ARCHITECTURE, AND ARCHAEOLOGY III, 2011, 8084
[3] Combined spectral-domain optical coherence tomography and hyperspectral imaging applied for tissue analysis: Preliminary results
Dontu, S.
Miclos, S.
Savastru, D.
Tautan, M.
APPLIED SURFACE SCIENCE, 2017, 417 : 119 - 123
[4] Non-invasive imaging of fluid dynamics with Doppler optical coherence tomography
Wang, RK
COMPLEX DYNAMICS, FLUCTUATIONS, CHAOS, AND FRACTALS IN BIOMEDICAL PHOTONICS, 2004, 5 (19): : 208 - 214
[5] Integration of a Spectral Domain Optical Coherence Tomography System into a Surgical Microscope for Intraoperative Imaging
Ehlers, Justis P.
Tao, Yuankai K.
Farsiu, Sina
Maldonado, Ramiro
Izatt, Joseph A.
Toth, Cynthia A.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2011, 52 (06) : 3153 - 3159
[6] Combined Depth Imaging Technique on Spectral-Domain Optical Coherence Tomography
Barteselli, Giulio
Bartsch, Dirk-Uwe
El-Emam, Sharif
Gomez, Maria Laura
Chhablani, Jay
Lee, Su Na
Conner, Laura
Freeman, William R.
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2013, 155 (04) : 727 - 732
[7] Non-invasive multimodal optical coherence and photoacoustic tomography for human skin imaging
Zhe Chen
Elisabet Rank
Kristen M. Meiburger
Christoph Sinz
Andreas Hodul
Edward Zhang
Erich Hoover
Micheal Minneman
Jason Ensher
Paul C. Beard
Harald Kittler
Rainer A. Leitgeb
Wolfgang Drexler
Mengyang Liu
Scientific Reports, 7
[8] Non-invasive multimodal optical coherence and photoacoustic tomography for human skin imaging
Chen, Zhe
Rank, Elisabet
Meiburger, Kristen M.
Sinz, Christoph
Hodul, Andreas
Zhang, Edward
Hoover, Erich
Minneman, Micheal
Ensher, Jason
Beard, Paul C.
Kittler, Harald
Leitgeb, Rainer A.
Drexler, Wolfgang
Liu, Mengyang
SCIENTIFIC REPORTS, 2017, 7
[9] Revolutionizing endoscopy: Non-invasive high-resolution imaging with time-domain optical coherence tomography
Jabbar, Abdul
Khalid, Ramna
Cabrera, Humberto
Mahmood, Nasir
Mehmood, Muhammad Qasim
UNCONVENTIONAL OPTICAL IMAGING IV, 2024, 12996
[10] Non-invasive characterization of microstructured optical fibers using Fourier domain optical coherence tomography
Jasapara, JC
OPTICS EXPRESS, 2005, 13 (04) : 1228 - 1233

← 1 2 3 4 5 →