Development of Venous Thromboembolism After COVID-19 mRNA-1273 Vaccine Inoculation

被引:4
|
作者
Mahgoub, Abdullahi E. [1 ,2 ]
Awuah, Dominic [1 ,2 ]
Hussain, MurtazaShabbir [1 ,2 ]
Deliwala, Smit [1 ,2 ]
Bachuwa, Ghassan [1 ,2 ]
Younas, Mariam [2 ,3 ]
机构
[1] Hurley Med Ctr, Internal Med, Flint, MI 48503 USA
[2] Michigan State Univ, Coll Human Med, Lansing, MI 48824 USA
[3] Hurley Med Ctr, Infect Dis, Flint, MI USA
关键词
covid vaccines; vaccine induced thrombosis; venous thromboembolism; mrna-1273; vaccine; covid-19; THROMBOSIS;
D O I
10.7759/cureus.22179
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 79-year-old man suddenly developed right lower extremity (RLE) pain and swelling a few days after receiving his 1st dose of the mRNA-1273 COVID-19 vaccine. Despite this, he proceeded to receive the 2nd dose of his mRNA-1273 COVID-19 vaccine. Investigations confirmed extensive acute deep venous thrombosis and a concurrent acute pulmonary embolism. Therapeutic anticoagulation was initiated and he was eventually discharged home on supplemental oxygen. The overall benefits of the vaccine in curbing severe disease overwhelmingly outweigh the handful of cases of reported adverse events. To our knowledge, this is one of the first few cases of provoked venous thrombosis after receiving the mRNA-1273 COVID-19 vaccine during the pharmacovigilance period.
引用
收藏
页数:7
相关论文
共 50 条
  • [41] COVID-19 mRNA-1273 vaccine induces production of vaccine-induced immune thrombotic thrombocytopenia antibodies
    Padmanabhan, Anand
    Kanack, Adam J.
    Kaplan, Robert B.
    Sangli, Swathi
    AMERICAN JOURNAL OF HEMATOLOGY, 2022, 97 (06) : E223 - E225
  • [42] COVID arm that appeared in the contralateral upper extremity after mRNA-1273 booster inoculation
    Sanomachi, Tomomi
    Okuma, Hitomi Sumiyoshi
    Yonemori, Kan
    INTERNATIONAL CANCER CONFERENCE JOURNAL, 2023, 12 (03) : 216 - 219
  • [43] Atypical Hemolytic Uremic Syndrome Occurring After Receipt of mRNA-1273 COVID-19 Vaccine Booster: A Case Report
    Claes, Kathleen J.
    Geerts, Inge
    Lemahieu, Wim
    Wilmer, Alexander
    Kuypers, Dirk R. J.
    Koshy, Priyanka
    Ombelet, Sara
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2023, 81 (03) : 364 - 367
  • [44] Safe re-immunization of mRNA-1273 COVID-19 vaccine after BNT162b2 mRNA COVID-19 vaccine-induced nonepisodic angioedema with eosinophilia
    Kampitak, Thatchai
    POSTGRADUATE MEDICAL JOURNAL, 2024, 100 (1188) : 769 - 770
  • [45] A Case of Autoimmune Hemolytic Anemia after the First Dose of COVID-19 mRNA-1273 Vaccine with Undetected Pernicious Anemia
    Jaydev, Fnu
    Kumar, Vinod
    Khatri, Jaikumar
    Shahani, Shobha
    Beganovic, Sead
    CASE REPORTS IN HEMATOLOGY, 2022, 2022
  • [46] Moderna's Covid-19 mRNA 1273 vaccine
    不详
    EXERCER-LA REVUE FRANCOPHONE DE MEDECINE GENERALE, 2021, (175): : 322 - 323
  • [47] Paucisymptomatic COVID-19 in lung transplant recipient following two doses of mRNA-1273 (Moderna) vaccine
    Marinelli, Tina
    Chaparro, Cecilia
    Humar, Atul
    Kumar, Deepali
    JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2021, 40 (09): : 862 - 862
  • [48] Familial thrombocytopenia flare-up following the first dose of mRNA-1273 Covid-19 vaccine
    Toom, Sudhamshi
    Wolf, Brian
    Avula, Akshay
    Peeke, Stephen
    Becker, Kevin
    AMERICAN JOURNAL OF HEMATOLOGY, 2021, 96 (05) : E134 - E135
  • [49] Acute tolerance of Moderna mRNA-1273 vaccine against COVID-19 in patients with cancer treated with radiotherapy
    Scoccianti, Silvia
    Delli Paoli, Camilla
    Leonulli, Barbara Grilli
    Paoletti, Lisa
    Alpi, Paolo
    Caini, Saverio
    Barca, Raffaella
    Fondelli, Simona
    Russo, Serenella
    Perna, Marco
    Pino, Maria Simona
    Martella, Francesca
    Furlan, Federica
    Bassetti, Andrea
    Fioretto, Luisa
    LANCET ONCOLOGY, 2021, 22 (09): : 1212 - 1214
  • [50] Cutaneous arteritis following mRNA-1273 Moderna COVID-19 vaccination
    Ogawa, T.
    Aitake, U.
    Nomura, T.
    JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2022, 36 (06) : E399 - E400