A randomized prospective study of microdose leuprolide versus ganirelix in in vitro fertilization cycles for poor responders

被引:71
|
作者
Schmidt, DW [1 ]
Bremner, T [1 ]
Orris, JJ [1 ]
Maier, DB [1 ]
Benadiva, CA [1 ]
Nulsen, JC [1 ]
机构
[1] Univ Connecticut, Ctr Hlth, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil,Ctr Adv Reprod S, Farmington, CT 06030 USA
关键词
D O I
10.1016/j.fertnstert.2004.10.053
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Forty-eight patients who met the criteria of poor response during prior gonadotropin stimulation were enrolled in a randomized prospective study comparing a gonadotropin-releasing hormone (GnRH) antagonist protocol, using ganirelix acetate, with a microdose GnRH agonist protocol for in vitro fertilization-embryo transfer (IVF-ET). This pilot study contributes to the literature of poor response IVF treatment protocols because the use of ganirelix appears to be as effective as the microdose protocol and may be a superior choice in terms of cost and convenience for the patient. (Fertil Steril (R) 2005;83:1568-71. (c) 2005 by American Society for Reproductive Medicine.)
引用
收藏
页码:1568 / 1571
页数:4
相关论文
共 50 条
  • [41] In Vitro Fertilization Outcomes in Superpoor Responders: Effect of Microdose Human Chorionic Gonadotropin Boost.
    Rubal, L.
    Opper, N.
    Bendikson, K.
    Chung, K.
    Paulson, R.
    FERTILITY AND STERILITY, 2010, 93 (05) : S21 - S21
  • [42] What is the optimum maximal gonadotropin dosage used in microdose flare-up cycles in poor responders?
    Berkkanoglu, Murat
    Ozgur, Kemal
    FERTILITY AND STERILITY, 2010, 94 (02) : 662 - 665
  • [43] Efficacy of aromatase inhibitors in poor responders undergoing in vitro fertilization
    Quintero, R
    Giudice, LC
    Westphal, L
    FERTILITY AND STERILITY, 2004, 81 : S28 - S28
  • [44] Poor responders in in vitro fertilization (IVF) therapy: the challenge continues
    Oehninger, S.
    FACTS VIEWS AND VISION IN OBGYN, 2011, 3 (02): : 101 - 108
  • [45] Pregnancies and births achieved from in vitro matured oocytes retrieved from poor responders undergoing stimulation in in vitro fertilization cycles
    Liu, JY
    Lu, GX
    Qian, Y
    Mao, YD
    Ding, W
    FERTILITY AND STERILITY, 2003, 80 (02) : 447 - 449
  • [46] What is the optimum maximal gonadotropin dosage used in microdose flare-up cycles in poor responders?
    Berkkanoglu, M.
    Agar, M.
    Ozgur, K.
    FERTILITY AND STERILITY, 2007, 88 : S281 - S281
  • [47] Growth hormone cotreatment for poor responders undergoing in vitro fertilization cycles: a systematic review and meta-analysis
    Cozzolino, Mauro
    Cecchino, Gustavo N.
    Troiano, Gianmarco
    Romanelli, Chiara
    FERTILITY AND STERILITY, 2020, 114 (01) : 97 - 109
  • [48] Clinical outcome of using ganirelix acetate versus a 4-day follicular phase leuprolide acetate protocol in unselected women undergoing in vitro fertilization
    Posada, MN
    Vlahos, NP
    Jurema, MW
    Bracero, NJ
    Wallach, EE
    Garcia, JE
    FERTILITY AND STERILITY, 2003, 80 (01) : 103 - 110
  • [49] Luteal phase support with 17α-hyduoxyprogesterone versus unsupported cycles in in vitro fertilization:: A comparative randomized study
    Abate, A
    Brigandi, A
    Abate, FG
    Manti, F
    Unfer, V
    Perino, M
    GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 1999, 48 (02) : 78 - 80
  • [50] Agonist "flare-up" versus antagonist in the management of poor responders undergoing in vitro fertilization treatment
    Mohamed, KA
    Davies, WAR
    Allsopp, J
    Lashen, H
    FERTILITY AND STERILITY, 2005, 83 (02) : 331 - 335