Modulation of fetal hemoglobin in sickle cell anemia

被引：9
|
作者：
Steinberg, MH
机构：
[1] Univ Mississippi, Sch Med, GV Sonny Montgomery Dept, Vet Affairs Med Ctr, Jackson, MS 39216 USA
[2] Univ Mississippi, Sch Med, Dept Med, Div Hematol, Jackson, MS 39216 USA
来源：
HEMOGLOBIN | 2001年 / 25卷 / 02期
关键词：
D O I：
10.1081/HEM-100104028
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A partial understanding of the pathophysiology of sickle cell disease has suggested one means of treatment-increasing the distribution and concentration of fetal hemoglobin in sickle erythrocytes. Although this can be accomplished clinically with drugs like hydroxyurea, a complete understanding of the molecular and cellular basis of fetal hemoglobin regulation may suggest new and better ways of attaining this goal.
引用
收藏
页码：195 / 211
页数：17
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