Acquired Resistance of EGFR-Mutant Lung Cancer to a T790M-Specific EGFR Inhibitor: Emergence of a Third Mutation (C797S) in the EGFR Tyrosine Kinase Domain

被引:201
|
作者
Yu, Helena A. [1 ,2 ]
Tian, Shaozhou K. [3 ]
Drilon, Alexander E. [1 ,2 ]
Borsu, Laetitia [3 ]
Riely, Gregory J. [1 ,2 ]
Arcila, Maria E. [3 ]
Ladanyi, Marc [3 ,4 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Dept Med, Div Solid Tumor Oncol, Thorac Oncol Serv, New York, NY 10021 USA
[2] Weill Cornell Med Coll, Dept Med, New York, NY USA
[3] Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10065 USA
[4] Mem Sloan Kettering Canc Ctr, Human Oncol & Pathogenesis Program, New York, NY 10021 USA
关键词
MECHANISMS; REVEALS;
D O I
10.1001/jamaoncol.2015.1066
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:981 / 983
页数:3
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