Estimation of the intake of anthocyanidins and their food sources in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

被引:106
|
作者
Zamora-Ros, Raul [1 ]
Knaze, Viktoria [1 ]
Lujan-Barroso, Leila [1 ]
Slimani, Nadia [2 ]
Romieu, Isabelle [2 ]
Touillaud, Marina [2 ]
Kaaks, Rudolf [3 ]
Teucher, Birgit [3 ]
Mattiello, Amalia [4 ]
Grioni, Sara [5 ]
Crowe, Francesca [6 ]
Boeing, Heiner [7 ]
Foerster, Jana [7 ]
Ramon Quiros, J. [8 ]
Molina, Esther [9 ]
Maria Huerta, Jose [10 ]
Engeset, Dagrun [11 ]
Skeie, Guri [11 ]
Trichopoulou, Antonia [12 ,13 ]
Dilis, Vardis [12 ,13 ]
Tsiotas, Konstantinos [12 ]
Peeters, Petra H. M. [14 ,15 ]
Khaw, Kay-Thee [16 ]
Wareham, Nicholas [17 ]
Bueno-de-Mesquita, Bas [18 ,19 ]
Ocke, Marga C. [18 ]
Olsen, Anja [20 ]
Tjonneland, Anne [20 ]
Tumino, Rosario [21 ,22 ]
Johansson, Gerd [23 ]
Johansson, Ingegerd [24 ]
Ardanaz, Eva [25 ]
Sacerdote, Carlotta [26 ,27 ]
Sonestedt, Emily [28 ]
Ericson, Ulrika [28 ]
Clavel-Chapelon, Francoise [29 ,30 ]
Boutron-Ruault, Marie-Christine [29 ,30 ]
Fagherazzi, Guy [29 ,30 ]
Salvini, Simonetta [31 ]
Amiano, Pilar [32 ]
Riboli, Elio [33 ]
Gonzalez, Carlos A. [1 ]
机构
[1] IDIBELL, Unit Nutr Environm & Canc, Canc Epidemiol Res Programme, Catalan Inst Oncol, Barcelona, Spain
[2] Int Agcy Res Canc, Dietary Exposure Assessment Grp, F-69372 Lyon, France
[3] German Canc Res Ctr, Dept Canc Epidemiol, D-6900 Heidelberg, Germany
[4] Univ Naples Federico II, Dept Clin & Expt Med, Naples, Italy
[5] Fdn IRCCS Ist Nazl Tumori, Nutr Epidemiol Unit, Milan, Italy
[6] Univ Oxford, Canc Epidemiol Unit, Oxford, England
[7] German Inst Human Nutr Potsdam Rehbrucke, Dept Epidemiol, Nuthetal, Germany
[8] Publ Hlth & Hlth Planning Directorate, Asturias, Spain
[9] Andalusian Sch Publ Hlth, Granada, Spain
[10] Murcia Reg Hlth Author, Dept Epidemiol, Murcia, Spain
[11] Univ Tromso, Dept Community Med, Tromso, Norway
[12] Univ Athens, Sch Med, WHO Collaborating Ctr Food & Nutr Policies, Dept Hyg Epidemiol & Med Stat, GR-11527 Athens, Greece
[13] Hellen Hlth Fdn, Athens, Greece
[14] Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands
[15] Univ London Imperial Coll Sci Technol & Med, Dept Epidemiol & Biostat, Sch Publ Hlth, Fac Med, London, England
[16] Univ Cambridge, Sch Clin Med, Cambridge, England
[17] MRC Epidemiol Unit, Cambridge, England
[18] Natl Inst Publ Hlth & Environm RIVM, Bilthoven, Netherlands
[19] UMCU, Dept Gastroenterol & Hepatol, Utrecht, Netherlands
[20] Danish Canc Soc, Inst Canc Epidemiol, Copenhagen, Denmark
[21] Civile MP Arezzo Hosp, Canc Registry, Ragusa, Italy
[22] Civile MP Arezzo Hosp, Histopathol Unit, Ragusa, Italy
[23] Umea Univ, Dept Clin Med & Publ Hlth Nutr Res, Umea, Sweden
[24] Umea Univ, Dept Odontol Cariol, Umea, Sweden
[25] Navarre Publ Hlth Inst, Pamplona, Spain
[26] Ctr Canc Prevent CPO Piemonte, Turin, Italy
[27] Human Genet Fdn HuGeF, Turin, Italy
[28] Lund Univ, Dept Clin Sci, Malmo, Sweden
[29] Inst Gustave Roussy, INSERM, Ctr Res Epidemiol & Populat Hlth, U1018, F-94805 Villejuif, France
[30] Paris S Univ, UMRS 1018, Villejuif, France
[31] Canc Res & Prevent Inst ISPO, Mol & Nutr Epidemiol Unit, Florence, Italy
[32] Basque Govt, Publ Hlth Dept Guipuzkoa, Inst Invest Sanitaria BioDonostia, San Sebastian, Spain
[33] Univ London Imperial Coll Sci Technol & Med, Dept Epidemiol Publ Hlth & Primary Care, London, England
基金
英国医学研究理事会; 英国惠康基金;
关键词
Anthocyanidins; Intake; Food sources; EPIC-Europe; DIETARY FLAVONOID INTAKE; HEART-DISEASE; RISK; POLYPHENOLS; WOMEN; SUPPLEMENTATION; CONSUMPTION; CALIBRATION; RATIONALE; BEVERAGES;
D O I
10.1017/S0007114511001437
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Anthocyanidins are bioactive flavonoids with potential health-promoting effects. These may vary among single anthocyanidins considering differences in their bioavailability and some of the mechanisms involved. The aim of the present study was to estimate the dietary intake of anthocyanidins, their food sources and the lifestyle factors (sex, age, BMI, smoking status, educational level and physisical activity) involved among twenty-seven centres in ten European countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Anthocyanidin intake and their food sources for 36 037 subjects, aged between 35 and 74 years, in twenty-seven redefined centres were obtained using standardised 24 h dietary recall software (EPIC-SOFT). An ad hoc food composition database on anthocyanidins (cyanidin, delphinidin, malvidin, pelargonidin, peonidin, petunidin) was compiled using data from the US Department of Agriculture and Phenol-Explorer databases and was expanded by adding recipes, estimated values and cooking factors. For men, the total anthocyanidin mean intake ranged from 19.83 (SE 1.53) mg/d (Bilthoven, The Netherlands) to 64.88 (SE 1.86) mg/d (Turin, Italy), whereas for women the range was 18.73 (SE 2.80) mg/d (Granada, Spain) to 44.08 (SE 2.45) mg/d (Turin, Italy). A clear south to north gradient intake was observed. Cyanidins and malvidins were the main anthocynidin contributors depending on the region and sex. Anthocyanidin intake was higher in non-obese older females, non-smokers, and increased with educational level and physical activity. The major food sources were fruits, wine, non-alcoholic beverages and some vegetables. The present study shows differences in both total and individual anthocyanidin intakes and various lifestyle factors throughout Europe, with some geographical variability in their food sources.
引用
收藏
页码:1090 / 1099
页数:10
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