Mixed States in Early-Onset Bipolar Disorder

被引：15

作者：

Saxena, Kirti ^{[1
,2
]}

Kurian, Sherin ^{[1
,2
]}

Saxena, Johanna ^{[1
,2
]}

Goldberg, Adam ^{[3
]}

Chen, Eugenia ^{[1
]}

Simonetti, Alessio ^{[1
,4
,5
,6
]}

机构：

[1] Baylor Coll Med, Menninger Dept Psychiat & Behav Sci, 1 Baylor Plaza, Houston, TX 77030 USA

[2] Texas Childrens Hosp, Dept Psychiat, Houston, TX 77030 USA

[3] Univ Texas Hlth Sci Ctr Houston, McGovern Med Sch, Dept Psychiat & Behav Sci, 1941 East Rd, Houston, TX 77054 USA

[4] Sapienza Univ Rome, Dept Neurol & Psychiat, Rome, Italy

[5] Ctr Lucio Bini, Rome, Italy

[6] Baylor Coll Med, Dept Psychiat, 1977 Butler Blvd,Suite E4-400, Houston, TX 77030 USA

来源：

PSYCHIATRIC CLINICS OF NORTH AMERICA | 2020年 / 43卷 / 01期

关键词：

Mixed states; Bipolar disorder; Children; Adolescents; Diagnosis; Comorbidity; Treatment; OPEN-LABEL TRIAL; I DISORDER; DOUBLE-BLIND; DIVALPROEX SODIUM; CHILDREN; ADOLESCENTS; PLACEBO; LITHIUM; DEPRESSION; ARIPIPRAZOLE;

D O I：

10.1016/j.psc.2019.10.009

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Pediatric bipolar disorder (PBD) is a severe and chronic illness. The occurrence of mixed symptoms might add further risk of recurrence of treatment resistance and suicidality. Early recognition and treatment of mixed symptoms might prevent illness progression and development of suicide attempts. This article provides an update on the epidemiology, clinical profile, and treatment of youth with PBD with mixed states. Mixed states in PBD are characterized by higher rates of suicide and more chronic symptoms, and are associated with younger age of onset and greater comorbidity. A careful assessment for mixed states using standardized criteria is essential.

引用

页码：95 / +

页数：18

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