Wound dressing from polyvinyl alcohol/chitosan electrospun fiber membrane loaded with OH-CATH30 nanoparticles

被引：125
|
作者：
Zou, Pengfei [1 ]
Lee, Wen-Hui [2 ,3 ]
Gao, Zhiqin [3 ]
Qin, Di [3 ]
Wang, Yuxia [1 ]
Liu, Jiao [1 ]
Sun, Tongyi [3 ]
Gao, Yuanyuan [1 ]
机构：
[1] Weifang Med Univ, Sch Pharm, Baotong Rd, Weifang 261053, Shandong, Peoples R China
[2] Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mech, Key Lab Bioact Peptide Yunnan Prov, Kunming 650223, Yunnan, Peoples R China
[3] Weifang Med Univ, Sch Biosci & Technol, Key Lab Biol Med Univ Shandong Prov, Baotong Rd, Weifang 261053, Shandong, Peoples R China
来源：
CARBOHYDRATE POLYMERS | 2020年 / 232卷 / 232期
基金：
中国国家自然科学基金;
关键词：
OH-CATH30; PVA; Wound healing; Nanofibers; Nanoparticles; ANTIMICROBIAL PEPTIDE OH-CATH30; IN-VITRO; NANOFIBROUS MEMBRANE; SILVER NANOPARTICLES; EFFICIENT STRATEGY; ANTIBACTERIAL; DRUG; ALGINATE; MATS; FABRICATION;
D O I：
10.1016/j.carbpol.2019.115786
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Novel nanomaterials have been developed for antimicrobial and wound healing applications. Here, we report the preparation of a polyvinyl alcohol/chitosan (PVA/CS) nanofiber with carboxymethyl chitosan nanoparticles (CMCS-OH30 NPs) encapsulating the antibacterial peptide OH-CATH30 (OH-30). The PVA/CS nanofibers containing OH-30 NPs (NP-30-NFs) obtained via electrospinning could achieve a secondary embedded OH-30. The effect of NP-30-NFs on the release of OH-30 was investigated through high-performance liquid chromatography. The antibacterial activities of NP-30-NFs against Escherichia coli and Staphylococcus aureus were studied by bacterial plate counting. NP-30-NFs containing different concentrations of NPs were applied to mouse skin wounds to determine their effectiveness in promoting wound healing. Results showed that NP-30-NFs exhibited antibacterial properties and promoted skin wound healing.
引用
收藏
页数：10
相关论文
共 50 条
  • [11] Incorporation of ZnO nanoparticles into heparinised polyvinyl alcohol/chitosan hydrogels for wound dressing application
    Khorasani, Mohammad Taghi
    Joorabloo, Alireza
    Moghaddam, Armaghan
    Shamsi, Hamidreza
    MansooriMoghadam, Zohreh
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 114 : 1203 - 1215
  • [12] Fabrication of chitosan/sericin/polyvinyl alcohol nanofiber with silver nanoparticles for wound dressing applications
    Devi, M. Gundhavi
    Karthick, S. Arun
    POLYMER ENGINEERING AND SCIENCE, 2024, 64 (09): : 4128 - 4143
  • [13] Electrospun polyvinyl alcohol membranes incorporated with green synthesized silver nanoparticles for wound dressing applications
    Augustine, Robin
    Hasan, Anwarul
    Nath, V. K. Yadu
    Thomas, Jince
    Augustine, Anitha
    Kalarikkal, Nandakumar
    Al Moustafa, Ala-Eddin
    Thomas, Sabu
    JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2018, 29 (11)
  • [14] Electrospun polyvinyl alcohol membranes incorporated with green synthesized silver nanoparticles for wound dressing applications
    Robin Augustine
    Anwarul Hasan
    V. K Yadu Nath
    Jince Thomas
    Anitha Augustine
    Nandakumar Kalarikkal
    Ala-Eddin Al Moustafa
    Sabu Thomas
    Journal of Materials Science: Materials in Medicine, 2018, 29
  • [15] Development and Evaluation of Fucoidan-Loaded Electrospun Polyvinyl Alcohol/Levan Nanofibers for Wound Dressing Applications
    Ismayilova, Natavan
    Zia, Muhammad Khaqan
    Akkaya, Hatice Selen
    Ulag, Songul
    Guldorum, Yeliz
    Oner, Ebru Toksoy
    Ince, Erol
    Duta, Liviu
    Gunduz, Oguzhan
    BIOMIMETICS, 2024, 9 (09)
  • [16] Developing curcumin loaded-magnetic montmorillonite nanoparticles/ polyvinyl alcohol/hyaluronic acid/chitosan nanofiber mats as a wound dressing
    Sayyar, Zahra
    Hosseini, Zahra
    Beheshtizadeh, Nima
    JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2024, 93
  • [17] Wound dressing materials with synergistic antibacterial activity from electrospun tri-component (chitosan/silver-NPs/polyvinyl alcohol) fiber mats
    Abdelgawad, Abdelrahman M.
    Hudson, Samuel M.
    Rojas, Orlando J.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [18] Characterizations of Centrifugal Electrospun Polyvinyl Alcohol/Sodium Alginate/Tamanu Oil/Silver Nanoparticles Wound Dressing
    Tran, Thi Phuong Anh
    Luong, Anh Hue
    Lin, Wei-Chih
    IEEE TRANSACTIONS ON NANOBIOSCIENCE, 2024, 23 (02) : 368 - 377
  • [19] Novel electrospun polyvinyl alcohol/chitosan/polycaprolactone-diltiazem hydrochloride nanocomposite membranes for wound dressing applications
    Etemadi, Niloofar
    Mehdikhani, Mehdi
    Huri, Pinar Yilgor
    Poursamar, Seyed Ali
    Rafienia, Mohammad
    EMERGENT MATERIALS, 2024, 7 (03) : 1103 - 1113
  • [20] Co-electrospun nanofibers of gelatin and chitosan-polyvinyl alcohol-eugenol for wound dressing applications
    Campa-Siqueiros, Paola, I
    Jesus Madera-Santana, Tomas
    Fernando Ayala-Zavala, Jesus
    Lopez-Cervantes, Jaime
    Monica Castillo-Ortega, Maria
    Jesus Herrera-Franco, Pedro
    Quintana-Owen, Patricia
    POLYMER BULLETIN, 2023, 80 (04) : 3611 - 3632
12345