retinopathy of prematurity;
screening;
expressed breast milk;
premature infant pain profile scale: PIPP;
TOPICAL ANESTHESIA;
EYE EXAMINATIONS;
RETINOPATHY;
D O I:
10.1093/tropej/fmu073
中图分类号:
R72 [儿科学];
学科分类号:
100202 ;
摘要:
Objective: To assess the effectiveness of expressed breast milk (EBM) on neonatal pain during screening for retinopathy of prematurity (ROP). Methods: Neonates who were on oral feeds undergoing ROP screening were included. Babies were randomized into intervention group (EBM + Standard practice) and control group. The standard practice is proparacaine, nesting and swaddling. Pain was assessed by PIPP scale, during and at 1 and 5 min after the procedure by the principal investigator who was blinded. Results: The groups were similar in baseline characteristics. The group receiving EBM had significantly lower PIPP scores during the procedure 12.7 +/- 1.69 compared to the control group 15.5 +/- 1.78 (p<0.05). The beneficial effect persisted at 1 min and 5 min after the procedure 6.20 +/- 1.9 vs. 12.4 +/- 2.54 (p <= 0.05) at 1 min; 3.2 +/- 1.5 and 6.85 +/- 2.4 (p<0.05) at 5 min. Conclusion: Oral EBM significantly reduces pain during and after ROP screening.