COVID-19 treatment by repurposing drugs until the vaccine is in sight

被引:61
|
作者
Phadke, Mrudula [1 ]
Saunik, Sujata [1 ,2 ]
机构
[1] Maharashtra Univ Hlth Sci, Govt Maharashtra, UNICEF, NHM, Nasik, Maharashtra, India
[2] Harvard Univ, ICS Govt Mah, Harvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA
关键词
D O I
10.1002/ddr.21666
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Corona virus disease (COVID-19) has created pandemic in the world as declared by WHO on March 12, 2020. It is a viral disease caused by SARS-CoV 2 virus and has affected large populations in over 120 countries. There is no specific treatment available and management is empirical. Until such time that an effective vaccine is available for COVID-19 viral infection, one can repurpose known therapeutic drug molecules such as angiotensin receptor 2 blocker, a commonly used antihypertensive drug, to control COVID-19 virus from gaining entry into the host cell by blocking the angiotensin receptor. Clinical trials should also be undertaken to use statins, which are lipid-lowering drugs but have anti-inflammatory and immunomodulatory properties to prevent acute lung injury in COVID-19 infection.
引用
收藏
页码:541 / 543
页数:3
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