Fistulizing Crohn's disease

被引：10
|
作者：
Felley, C
Mottet, C
Juillerat, P
Froehlich, F
Burnand, B
Vader, JP
Michetti, P
Gonvers, JJ
机构：
[1] Univ Lausanne, Med Ctr, Div Gastroenterol & Hepatol, CH-1011 Lausanne, Switzerland
[2] Univ Basel, Gastrointestinal Dept, Basel, Switzerland
[3] Univ Lausanne, Inst Social & Prevent Med, Lausanne, Switzerland
来源：
DIGESTION | 2005年 / 71卷 / 01期
关键词：
Crohn's disease; fistula; antibiotics; azathioprine; infliximab; methotrexate; cyclosporine; tacrolimus; internal fistulas; surgery;
D O I：
10.1159/000083868
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Fistulas are common in Crohn's disease. A population-based study has shown a cumulative risk of 33% after 10 years and 50% after 20 years. Perianal fistulas were the most common (54%). Medical therapy is the main option for perianal fistula once abscesses, if present, have been drained, and should include antibiotics ( both ciprofloxacin and metronidazole) and immunomodulators. Infliximab should be reserved for refractory patients. Surgery is often necessary for internal fistulas. Copyright (C) 2005 S. Karger AG, Basel.
引用
收藏
页码：26 / 28
页数：3
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