Synthesis of methyl 9-mesityl-12-aryl-11-oxo-7,8,9,10,11,12-hexahydrobenzo[a]- acridine-10-carboxylates

被引:1
|
作者
Kozlov, N. G. [1 ]
机构
[1] Natl Acad Sci Belarus, Inst Phys Organ Chem, Minsk 220072, BELARUS
关键词
Acridine; Aromatic Aldehyde; Mesityl; Isomer Mixture; Aryl Substituent;
D O I
10.1134/S1070428011110091
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
By condensation of 2-naphthylamine with methyl 2-mesityl-4,6-dioxocyclohexanecarboxylate and aromatic aldehydes new acridine derivatives were synthesized. The condensation in ethanol proceeded regiospecifi cally with moderate stereoselectivity resulting in a mixture of cis- and trans-methyl 9-mesityl-12-aryl-11-oxo-7,8,9,10,11,12-hexahydrobenzo[a]acridine-10-carboxylate (similar to 40: 60%).
引用
收藏
页码:1710 / 1714
页数:5
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