Expression of Anti-Microbial Peptide LL-37 Correlates to the Activation of Type I Interferon Pathway in Patients with Idiopathic Inflammatory Myopathies

被引:0
|
作者
Lu, Xin
Tang, Quan [1 ]
Lindh, Monica [2 ]
Agerberth, Birgitta [3 ]
Dastmalchi, Maryam [4 ]
Lundberg, Ingrid E. [5 ]
Wick, Cecilia [6 ]
机构
[1] Karolinska Univ Hosp, Karolinska Inst, Dept Med, Rheumatol Unit, Stockholm, Sweden
[2] Karolinska Univ Hosp Huddinge, Karolinska Inst, Div Clin Microbiol, Dept Lab Med, Stockholm, Sweden
[3] Karolinska Inst, Dept Med Biochem & Biophys, Chem 1, Stockholm, Sweden
[4] Karolinska Univ Hosp Solna, Karolinska Inst, Dept Med, Unit Rheumatol, Stockholm, Sweden
[5] Karolinska Univ Hosp, Karolinska Inst, Dept Med, Rheumatol Unit, Stockholm, Sweden
[6] Karolinska Inst, Dept Med, Rheumatol Unit, Stockholm, Sweden
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
278
引用
收藏
页数:2
相关论文
共 25 条
  • [1] THE ANTIMICROBIAL PEPTIDE LL-37 AND TYPE I INTERFERON IN IDIOPATHIC INFLAMMATORY MYOPATHIES
    Lu, X.
    Tang, Q.
    Lindroos, E.
    Lindh, M.
    Agerberth, B.
    Lundberg, I.
    Wick, C.
    ANNALS OF THE RHEUMATIC DISEASES, 2016, 75 : 736 - 736
  • [2] The anti-microbial peptide LL-37 inhibits the activation of dendritic cells by TLR ligands
    Kandler, Kerstin
    Shaykhiev, Renat
    Kleemann, Peter
    Klescz, Frank
    Lohoff, Michael
    Vogelmeier, Claus
    Bals, Robert
    INTERNATIONAL IMMUNOLOGY, 2006, 18 (12) : 1729 - 1736
  • [3] The anti-microbial peptide LL-37 changes the secretion pattern and intracellular activation of keratinocytes
    Sigurgrimsdottir, Hildur
    Freysdottir, Jona
    Ludviksson, Bjorn R.
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2019, 90 (06)
  • [4] Electrochemical screening of anti-microbial peptide LL-37 interaction with phospholipids
    Neville, Frances
    Gidalevitz, David
    Kale, Girish
    Nelson, Andrew
    BIOELECTROCHEMISTRY, 2007, 70 (02) : 205 - 213
  • [5] Statins influence epithelial expression of the anti-microbial peptide LL-37/hCAP-18 independently of the mevalonate pathway
    Luthje, P.
    Walker, S.
    Kamolvit, W.
    Mohanty, S.
    Putsep, K.
    Brauner, A.
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2019, 195 (02): : 265 - 276
  • [6] Autoantibody Specificities and Type I Interferon Pathway Activation In Idiopathic Inflammatory Myopathies
    Vosslamber, Saskia
    Ekholm, Louise
    Tjarnlund, Anna
    de Jong, T. D.
    Plestilova, Lenka
    Klein, Martin
    Charles, Peter J.
    Voskuyl, A. E.
    Bultink, Irene
    Pegtel, Michiel
    Vencovsky, J.
    Lundberg, Ingrid E.
    Verweij, Cornelis L.
    ARTHRITIS AND RHEUMATISM, 2013, 65 : S803 - S803
  • [7] Autoantibody Specificities and Type I Interferon Pathway Activation in Idiopathic Inflammatory Myopathies
    Ekholm, L.
    Vosslamber, S.
    Tjarnlund, A.
    de Jong, T. D.
    Betteridge, Z.
    McHugh, N.
    Plestilova, L.
    Klein, M.
    Padyukov, L.
    Voskuyl, A. E.
    Bultink, I. E. M.
    Pegtel, D. Michiel
    Mavragani, C. P.
    Crow, M. K.
    Vencovsky, J.
    Lundberg, I. E.
    Verweij, C. L.
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2016, 84 (02) : 100 - 109
  • [8] The potentials of short fragments of human anti-microbial peptide LL-37 as a novel therapeutic modality for diseases
    Chen, Keqiang
    Gong, Wanghua
    Huang, Jiaqiang
    Yoshimura, Teizo
    Wang, Ji Ming
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2021, 26 (11): : 1362 - 1372
  • [9] The host defense peptide LL-37 a possible inducer of the type I interferon system in patients with polymyositis and dermatomyositis
    Lu, Xin
    Tang, Quan
    Lindh, Monica
    Dastmalchi, Maryam
    Alexanderson, Helene
    Silwerfeldt, Karin Popovic
    Agerberth, Birgitta
    Lundberg, Ingrid E.
    Wick, Cecilia
    JOURNAL OF AUTOIMMUNITY, 2017, 78 : 46 - 56
  • [10] Human anti-microbial cathelicidin peptide LL-37 suppresses the LPS-induced apoptosis of endothelial cells
    Suzuki, Kaori
    Murakami, Taisuke
    Kuwahara-Arai, Kyoko
    Tamura, Hiroshi
    Hiramatsu, Keiichi
    Nagaoka, Isao
    INTERNATIONAL IMMUNOLOGY, 2011, 23 (03) : 185 - 193