Synthesis of novel thiopyrimidines: an investigation of anti-tubercular and antimicrobial activity

被引：12

作者：

Haveliwala, Dhaval D. ^{[1
]}

Kamdar, Nimesh R. ^{[1
]}

Mistry, Prashant T. ^{[1
]}

Patel, Saurabh K. ^{[1
]}

机构：

[1] Veer Narmad S Gujarat Univ, Dept Chem, Surat 395007, Gujarat, India

来源：

JOURNAL OF SULFUR CHEMISTRY | 2011年 / 32卷 / 05期

关键词：

thiopyrimidines; dithiopyrimidines; chromone; anti-tubercular activity; antimicrobial activity; PYRIDINE; DERIVATIVES;

D O I：

10.1080/17415993.2010.523894

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A variety of novel sulfur-containing tricyclic pyrimidine derivatives have been synthesized via the reaction of 2-amino-4-oxo-4H-chromene-3-carbonitriles 3(a-f) with different reagents and characterized by IR, H-1 NMR, C-13 NMR, mass spectrometry and elemental analysis. The anti-tubercular and antimicrobial activities of the synthesized compounds were investigated. [GRAPHICS] .

引用

页码：451 / 462

页数：12

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